formoguanamine

01/01/1988 - "Chicks blinded with formoguanamine do not develop lid suture myopia."
07/01/1995 - "Formoguanamine-induced inhibition of deprivation myopia in chick is accompanied by choroidal thinning while retinal function is retained."
01/01/1988 - "The involvement of the retina in avian lid suture myopia was investigated by use of formoguanamine (FG), which induces blindness in chicks, characterized by damage to the retinal pigment epithelium and photoreceptor layers. "
01/01/1999 - "Special attention is focused on the following substances inhibiting the progress of experimental myopia: apomorphine, reserpine, 6-hydroxydopamine, atropine, pirenzepine, chlorpyrifos, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid, kainic acid, naloxane, formoguanamine, gentamicin, sodium iodate, central and peripheral antagonist of vasoactive intestinal polypeptide, basic fibroblast growth factor. "
01/01/2005 - "Additionally, the following substances inhibiting the progress of experimental myopia are discussed: atropine, oxyphenonium, pirenzepine, chlorpyrifos, apomorphine, reserpine, 6-hydroxy dopamine, dextromethorphan, MK-801, APV, bicuculline, SR95531, CACA, TPMPA, dextrorphanol, levorphanol, D- and L-naloxane, L-NAME, formoguanamine, beta-xyloside, central and peripheral antagonists of VIP, and basic fibroblast growth factor. "

12/01/2002 - "Formoguanamine (2,4-diamino-s-triazine) was known to be an effective chemical agent in inducing blindness in poultry chicks, but not in adult birds. "
12/01/2002 - "Induction of blindness by formoguanamine hydrochloride in adult male roseringed parakeets (Psittacula krameri)."
01/01/1988 - "The involvement of the retina in avian lid suture myopia was investigated by use of formoguanamine (FG), which induces blindness in chicks, characterized by damage to the retinal pigment epithelium and photoreceptor layers. "

03/01/1995 - "Formoguanamine is a triazine drug which induces hyperornithinemic symptoms in the chick eye similar to those seen in human gyrate atrophy. "

10/01/1985 - "From these findings it may be concluded that formoguanamine primarily damages the physiological functions of retinal pigment epithelium and photoreceptors and results in irreversible retinal detachment in newly hatched chicks."
10/01/1985 - "Histological examination of the formoguanamine-treated chicks revealed characteristic degeneration of pigment epithelium and photoreceptors, acute retinal detachment and a secondary gliosis in the outer nuclear layer. "

10/01/1985 - "Histological examination of the formoguanamine-treated chicks revealed characteristic degeneration of pigment epithelium and photoreceptors, acute retinal detachment and a secondary gliosis in the outer nuclear layer. "