1-amino-2,4-dibromoanthraquinone

intermediate in the production of dyes

Also Known As:

ADBAQ

Networked: 4 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Anthracenes: 12
        Anthrones: 12
        Anthraquinones: 788
        1-amino-2,4-dibromoanthraquinone: 4
- Quinones: 434
  - Anthraquinones: 788
    - 1-amino-2,4-dibromoanthraquinone: 4
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Anthracenes: 12
    - Anthrones: 12
      - Anthraquinones: 788
        1-amino-2,4-dibromoanthraquinone: 4

Experts

1.	Bian, Haitao: 1 article (04/2009)
2.	Cai, Xiyun: 1 article (04/2009)
3.	Chen, Jingwen: 1 article (04/2009)
4.	Hao, Ce: 1 article (04/2009)
5.	Lin, Jing: 1 article (04/2009)
6.	Wang, Ying: 1 article (04/2009)
7.	Wang, Zhen: 1 article (04/2009)
8.	Devereux, T R: 1 article (07/2001)
9.	Hayashi, S: 1 article (07/2001)
10.	Hong, H H: 1 article (07/2001)

Related Diseases

1.	Carcinogenesis 08/01/1996 - "NTP Toxicology and Carcinogenesis Studies of 1-Amino-2,4-Dibromoanthraquinone (CAS No. 81-49-2) in F344/N Rats and B6C3F1 Mice (Feed Studies)." 03/15/1986 - "1-Amino-2,4-dibromoanthraquinone (ADBAQ), an intermediate in the production of commercial dyes for wool, silk, and synthetic fibers, was selected for toxicology and carcinogenesis studies in two rodent species. "
2.	Neoplasms (Cancer) 07/01/2001 - "The present study indentified genetic alterations in H-ras and K-ras proto-oncogenes in ADBAQ-induced tumors. " 07/01/2001 - "In a 2-year study with dietary exposure to 10,000 or 20,000 ppm ADBAQ, increased incidence of forestomach and lung tumors were observed in B6C3F1 mice. " 08/01/1996 - "CONCLUSIONS: Under the conditions of these 2-year feed studies, there was clear evidence of carcinogenic activity of 1-amino-2,4-dibromoanthraquinone in male and female F344/N rats based on increased incidences of neoplasms in the liver, large intestine, kidney, and urinary bladder. " 08/01/1996 - "Pathology Findings In the 2-year study, 1-amino-2,4-dibromoanthraquinone was associated with significant chemical-related increases in the incidences of benign and malignant neoplasms in the liver, forestomach, and lung of males and females. " 08/01/1996 - "Pathology Findings In the 2-year study, 1-amino-2,4-dibromoanthraquinone was associated with significant chemical-related increases in the incidences of benign and malignant neoplasms in the liver, large intestine, kidney, and urinary bladder of males and females. "
3.	Body Weight (Weight, Body) 08/01/1996 - "DISPOSITION AND METABOLISM STUDIES: Adult male F344/N rats were given [14C]-labeled 1-amino-2,4-dibromoanthraquinone as a single intravenous dose of 0.4 mg/kg body weight or as a single oral dose of 2, 23, 118, 814, or 1,473 mg/kg. A 6-hour bile cannulation study was also performed. "
4.	Liver Cell Adenoma (Hepatocellular Adenoma) 08/01/1996 - "After 9 months of dietary exposure to a concentration of 20,000 ppm 1-amino-2,4-dibromoanthraquinone, hepatocellular adenoma and carcinoma occurred in males and females. "
5.	Photosensitivity Disorders (Photodermatitis) 04/01/2009 - "These experimental results demonstrate that photosensitization is the potential mechanism of photoinduced toxicity of ADBAQ to D. "

Related Drugs and Biologics

1.	1-amino-2,4-dibromoanthraquinone
2.	Silk
3.	Coloring Agents (Dyes)
4.	Codon (Codons)
5.	Adenine