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nomegestrol

19-nor-progesterone derivative; structure given in UD

Also Known As:

Lutenyl; 19-Norpregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-

Networked: 8 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnadienes
        Megestrol: 112
        nomegestrol: 8

Experts

1.	AbiJaoude, Samiya: 1 article (01/2021)
2.	Cornu, Philippe: 1 article (01/2021)
3.	Kalamarides, Michel: 1 article (01/2021)
4.	Marijon, Pauline: 1 article (01/2021)
5.	Peyre, Matthieu: 1 article (01/2021)
6.	Roblot, Paul: 1 article (01/2021)
7.	Tran, Suzanne: 1 article (01/2021)
8.	Fehm, T: 1 article (10/2013)
9.	Ma, Q: 1 article (10/2013)
10.	Mueck, A O: 1 article (10/2013)

Related Diseases

1.	Dyslipidemias (Dyslipidemia) 12/01/1998 - "In this study including 26 patients with dyslipoproteinemia classified IIa, we evaluated biochemical and clinical safety of Nomegestrol acetate (Lutenyl) used for its antigonadotrophin property. "
2.	Meningioma (Meningiomas) 01/01/2021 - "We then demonstrate the sustained growth of intraosseous hormone-associated meningiomas after cessation of promesgestone and nomegestrol, independently of the intracranial portion, which concurrently decreased in size in the second case or was resected at the time of nomegestrol withdrawal in the third case, thus giving new insights into the tumorigenesis mechanisms of hormone-associated intraosseous meningiomas." 01/01/2021 - "We report three observations on the natural history of hormone-associated intraosseous meningiomas, showing in a first patient that those tumors may grow rapidly under nomegestrol. " 10/01/2022 - "We don´t have elements to scare women who use oral contraceptives based on nomegestrol or chlormadinone about the risk of meningioma. " 10/01/2022 - "To report the results of systematic meningioma screening program implemented by French authorities in patients exposed to progestin therapies (cyproterone (CPA), nomegestrol (NA), and chlormadinone (CMA) acetate). "
3.	Carcinogenesis 01/01/2021 - "We then demonstrate the sustained growth of intraosseous hormone-associated meningiomas after cessation of promesgestone and nomegestrol, independently of the intracranial portion, which concurrently decreased in size in the second case or was resected at the time of nomegestrol withdrawal in the third case, thus giving new insights into the tumorigenesis mechanisms of hormone-associated intraosseous meningiomas." 10/01/2013 - "Certain synthetic progestins can increase the proliferation of PGRMC1-overexpressing breast cancer cells and may thus be involved in tumorigenesis, while progesterone and certain synthetic progestins such as nomegestrol or chlormadinone acetate react neutrally. "
4.	Venous Thromboembolism 12/01/2022 - "To compare the risk of venous thromboembolism (VTE) among young women for nine combined oral contraceptives (COCs), including progestogens with an as yet unclear risk of VTE such as chlormadinone and nomegestrol, using COCs containing levonorgestrel with low ethinylestradiol (<50 μg) as a reference. "
5.	Neoplasms (Cancer) 01/01/2021 - "We report three observations on the natural history of hormone-associated intraosseous meningiomas, showing in a first patient that those tumors may grow rapidly under nomegestrol. "

Related Drugs and Biologics

1.	nomegestrol acetate
2.	Chlormadinone Acetate (Chlormadinone)
3.	Progestins (Progestagens)
4.	Progesterone Congeners
5.	Levonorgestrel (Plan B)
6.	Progesterone
7.	Hormones (Hormone)
8.	Cyproterone
9.	Combined Oral Contraceptives
10.	Oral Contraceptives

Related Therapies and Procedures

1.	Therapeutics