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N-methylglucosamine

RN given refers to (D)-isomer

Also Known As:

N-methyl glucosamine chlorine e6 salt; N-methylglucosamine, (L)-isomer; photodithazine

Networked: 10 relevant articles (2 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Amino Sugars: 110
  - Hexosamines: 733
    - Glucosamine: 1771
      - N-methylglucosamine: 10

Experts

1.	Ferreira-Strixino, Juliana: 2 articles (06/2021 - 08/2017)
2.	Fontana, Leticia Correa: 1 article (06/2021)
3.	Pinto, Juliana Guerra: 1 article (06/2021)
4.	Santos Vitorio, Gabrielle Dos: 1 article (06/2021)
5.	de Almeida, Rainara Moreno Sanches: 1 article (06/2021)
6.	Alonso, Gabriela Caroline: 1 article (12/2020)
7.	Alves, Fernanda: 1 article (12/2020)
8.	Bagnato, Vanderlei Salvador: 1 article (12/2020)
9.	Carmello, Juliana Cabrini: 1 article (12/2020)
10.	Mima, Ewerton Garcia de Oliveira: 1 article (12/2020)

Related Diseases

1.	Wounds and Injuries (Trauma) 09/01/2020 - "Microbiological analysis revealed that the photoactivation of photodithazine and its complexes suppressed the associated microflora in vivo and inhibited suppurative inflammation in the wounds. " 01/01/2014 - "The goal of this study was to evaluate the action of the PDT in the inactivation in vitro of microorganisms coming from infected wounds, using methylene blue (MB) and photodithazine (PDZ) as the PS and comparing the efficacy of these two compounds for PDT on bacteria. " 09/01/2020 - "We studied antibacterial and pro-regenerative effects of photodynamic therapy (PDT) performed with water solutions of photodithazine and its complexes with Pluronic F127 and chitosan in rat model of full thickness wound (n = 24) infected by an associated Gram-negative and Gram-positive bacteria culture. "
2.	Neoplasms (Cancer) 01/01/2018 - "Using fluorescence imaging in vivo we found that injection to mice of Ce6 in a formulation with PVA resulted in a higher tumor-to-normal ratio and greater photobleaching when compared with either the use of Ce6 alone, or with the effects of Photodithazine. " 01/01/2018 - "The purpose of the present study was to explore the efficacy of PDT with the formulation of the photosensitizer chlorin e6 (Ce6) in combination with polyvinyl alcohol (PVA) in comparison with Ce6 alone and with the clinical drug, Photodithazine in a mouse tumor model. "
3.	Gliosarcoma 08/01/2017 - "Photodithazine photodynamic effect on viability of 9L/lacZ gliosarcoma cell line." 06/01/2021 - "The aim of this study was to analyze the effects of PDT with Photodithazine (PDZ) in the treatment of gliosarcoma, using 9 L/lacZ cells and serial concentrations of 200 μg/mL to 3.1 μg/mL of PDZ. " 08/01/2017 - "The aim of this study is to observe the PDT action in gliosarcoma cell using a chlorin (Photodithazine, PDZ). "
4.	Phototoxic Dermatitis (Phototoxicity) 06/01/2015 - "In this study, hypericin and two other photosensitizers, a hematoporphyrin derivative (Photogem(®); PG) and a chlorin derivative (Photodithazine(®); PZ), were compared in terms of their phototoxicity toward two cell lines, HEp-2 and Vero. "
5.	Denture Stomatitis 12/01/2020 - "This randomized clinical trial assessed antimicrobial Photodynamic Therapy (aPDT) mediated by Photodithazine (PDZ) to treat patients with denture stomatitis (DS). " 12/01/2020 - "A randomized clinical trial evaluating Photodithazine-mediated Antimicrobial Photodynamic Therapy as a treatment for Denture stomatitis."

Related Drugs and Biologics

1.	1-phenyl-3,3-dimethyltriazene (PDT)
2.	Photosensitizing Agents (Photosensitizers)
3.	Polyvinyl Alcohol
4.	Methylene Blue (Methylthioninium Chloride)
5.	phytochlorin
6.	chlorin
7.	Hematoporphyrin Derivative
8.	hypericin
9.	Photogem
10.	Chitosan

Related Therapies and Procedures

1.	Photochemotherapy (Photodynamic Therapy)