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D 15413
structure given in first source
Also Known As:
4-chloro-2-(2,6-dichloro-4-hydroxyphenyl)-1-ethyl-6-hydroxyindole; D-15413
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Indoles: 200
D 15413: 2
Related Diseases
1.
Neoplasms (Cancer)
01/01/1985 - "
D 15413 was also active against MNU-induced rat mammary tumors and transplanted MXT tumors of the mouse.
"
07/01/1987 - "
Two antiestrogenic phenylindoles (D 16726 and D 15413) were tested for their prostatic tumor-inhibiting activity.
"
01/01/1985 - "
The inhibitory effect of 4-chloro-2-(2,6-dichloro-4-hydroxyphenyl)-1-ethyl-6-hydroxyindole (D 15413) on estrogen-dependent mammary tumors.
"
01/01/1985 - "
The antineoplastic activity of 4-chloro-2-(2,6-dichloro-4-hydroxyphenyl)-1-ethyl-6-hydroxyindole (D 15413) was determined in several estrogen-dependent mammary tumor models.
"
07/01/1987 - "
The tumor-inhibiting activity of D 16726 and D 15413 on the androgen-dependent R 3327 Dunning prostatic carcinoma and the human prostatic tumor PC 82 implanted in nude mice equals that of castration or of diethylstilbestrol.
"
2.
Carcinoma (Carcinomatosis)
07/01/1987 - "
The tumor-inhibiting activity of D 16726 and D 15413 on the androgen-dependent R 3327 Dunning prostatic carcinoma and the human prostatic tumor PC 82 implanted in nude mice equals that of castration or of diethylstilbestrol.
"
3.
Breast Neoplasms (Breast Cancer)
01/01/1985 - "
In vitro, the growth of estrogen receptor positive MCF-7 breast cancer cells was inhibited by D 15413 (10(-8) - 10(-5) M).
"
Related Drugs and Biologics
1.
D 15413
2.
Estrogen Receptors
3.
Estrogens (Estrogen)
4.
Diethylstilbestrol (Stilbestrol)
5.
Antineoplastic Agents (Antineoplastics)
6.
Androgens
7.
zindoxifene
Related Therapies and Procedures
1.
Castration