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protein-histidine kinase (histidine kinase)

Subscribe to New Research on protein-histidine kinase

StyS is component of regulatory system in Pseudomonas (see StyR protein); SasS involved in transduction of starvation and cell density inputs; hknA isolated from Bacillus thuringiensis; ciaH isolated from Streptococcus pneumoniae;

Also Known As:

histidine kinase; histidine protein kinase; protein-histidine pros-kinase; protein-histidine tele-kinase; AHK2 protein, Arabidopsis; AHK3 protein, Arabidopsis; HK1 protein, Zea mays; HK2 protein, Zea mays; HK3 protein, Zea mays; MAK1 histidine kinase; MAK2 histidine kinase; MAK3 histidine kinase; Phk1 protein, S pombe; Phk2 protein, S pombe; Phk3 protein, S pombe; ZmHK1 protein; ZmHK2 protein; histidine kinase 2, Arabidopsis; histidine kinase 3, Arabidopsis; histone H4 histidine kinase; mak1 protein, S pombe; mak2 protein, S pombe; mak3 protein, S pombe; protein kinase (histidine), pros-kinase; protein kinase (histidine), tele-kinase; sensor histidine kinase

Networked: 58 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes
- Enzymes: 34502
  - Transferases: 4296
    - Phosphotransferases: 30637
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9706
        protein-histidine kinase: 58

Experts

1.	Yang, Mengmeng: 3 articles (01/2011 - 08/2006)
2.	Kaetzel, David M: 3 articles (01/2011 - 08/2006)
3.	Steeg, Patricia S: 3 articles (08/2008 - 08/2002)
4.	Qu, Di: 2 articles (03/2012 - 01/2006)
5.	Wu, Yang: 2 articles (03/2012 - 01/2006)
6.	Attwood, Paul V: 2 articles (02/2012 - 11/2004)
7.	Besant, Paul G: 2 articles (02/2012 - 11/2004)
8.	Fujita, Masaya: 2 articles (11/2011 - 08/2010)
9.	Eswaramoorthy, Prahathees: 2 articles (11/2011 - 08/2010)
10.	McCorkle, Joseph R: 2 articles (01/2011 - 08/2006)

Related Diseases

1.	Shock 04/01/2015 - "Two-tiered histidine kinase pathway involved in heat shock and salt sensing in the general stress response of Sphingomonas melonis Fr1." 01/01/2014 - "Cold shock induced the expression of the genes encoding the histidine kinase (clo3403) and the response regulator (clo3404) by more than 100-fold after 5 h relative to their expression in a nonshocked culture at the corresponding time point. " 08/06/2010 - "DesK is a sensor histidine kinase (HK) that allows Bacillus subtilis to respond to cold shock, triggering the adaptation of membrane fluidity via transcriptional control of a fatty acid desaturase. " 07/01/2005 - "The histidine kinase Hik34 is involved in thermotolerance by regulating the expression of heat shock genes in synechocystis." 04/04/2003 - "This group included certain heat-shock genes, genes for subunits of the sulfate transport system, and the hik34 gene for a histidine kinase. "
2.	Neoplasm Metastasis (Metastasis) 02/01/2003 - "We hypothesize that a histidine protein kinase activity of Nm23 underlies its suppression of metastasis, and identify candidate substrates. " 08/30/2002 - "The metastasis-suppressive activity of Nm23-H1 was previously correlated with its in vitro histidine protein kinase activity, but physiological substrates have not been identified. " 01/01/2014 - "NM23-H1 (also known as NME1) was the first identified metastasis suppressor, which displays a nucleoside diphosphate kinase (NDPK) and histidine protein kinase activity. " 11/01/2007 - "NM23-H1 is a multifunctional protein, which, in addition to limiting metastasis, has DNase and histidine protein kinase activities. " 08/30/2002 - "Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway."
3.	Infection 03/01/2015 - "Previously, Brucella abortus light-sensing histidine kinase was identified as important for cellular infection. " 07/01/2012 - "FsrC is the membrane-bound histidine kinase component of the Fsr two-component signal transduction system involved in quorum sensing in the hospital-acquired infection agent Enterococcus faecalis. " 04/01/2012 - "Arabidopsis histidine kinase 5 regulates salt sensitivity and resistance against bacterial and fungal infection." 03/01/2012 - "To evaluate the efficacies of six derivatives of Compound 2, a novel YycG histidine kinase inhibitor with the thiazolidione core structure in the treatment of medical device-related biofilm infections. " 01/01/2006 - "Structure-based discovery of inhibitors of the YycG histidine kinase: new chemical leads to combat Staphylococcus epidermidis infections."
4.	Starvation 10/01/2012 - "The phosphotransferase protein EIIA(Ntr) modulates the phosphate starvation response through interaction with histidine kinase PhoR in Escherichia coli." 11/01/2011 - "It is believed that the N-terminal sensor domain of the cytoplasmic histidine kinase KinA is responsible for detection of the sporulation-specific signal(s) that appears to be produced only under starvation conditions. " 12/01/1997 - "This gene is predicted to encode a sensor histidine protein kinase that appears to be a key element in the transduction of starvation and cell density inputs. " 08/01/1990 - "PhoR protein is a histidine protein kinase, induced in Pi starvation and is a transmembrane protein. " 08/01/2010 - "Upon nutrient starvation, the Gram-positive bacterium Bacillus subtilis switches from growth to sporulation by activating a multicomponent phosphorelay consisting of a major sensor histidine kinase (KinA), two phosphotransferases (Spo0F and Spo0B) and a response regulator (Spo0A). "
5.	Coma (Comas) 02/20/2001 - "The response regulator ComA is primarily activated by ComP, a histidine kinase that mediates response to nutrient conditions and cell density, and the activated ComA is required for transcription of the srf operon, which is essential for the development of genetic competence and surfactin production. " 01/01/2001 - "In the presence of ComX, the membrane-localized ComP histidine kinase activates the response regulator ComA. " 02/01/2009 - "In liquid cultures, the histidine kinase ComP, and the response regulator ComA, respond to secreted pheromones ComX and CSF (encoded by phrC) in order to control production of surfactin synthases and ComS (competence regulator). " 08/01/2005 - "In Bacillus subtilis, a quorum response is mediated by a secreted 10-amino-acid modified peptide (ComX pheromone) that activates a receptor histidine kinase (ComP) that activates a response regulator transcription factor (ComA). " 01/01/2004 - "The competence quorum-sensing system of Bacillus subtilis consists of two-component regulatory proteins, ComP (histidine kinase) and the response regulator, ComA, an extracellular pheromone (ComX), and a protein that is needed for the proteolytic cleavage and modification of pre-ComX (ComQ). "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Phosphotransferases (Kinase)
3.	Staphylococcal Protein A (A, Protein)
4.	Nucleoside-Diphosphate Kinase
5.	Exonucleases (3' 5' Exonuclease)
6.	Protein Isoforms (Isoforms)
7.	Transcription Factors (Transcription Factor)
8.	KSR-1 protein kinase
9.	Cysteine Proteases (Cysteine Protease)
10.	Lysophosphatidic Acid Receptors