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hemopexin receptor

Also Known As:

haemopexin receptors; receptor, hemopexin

Networked: 5 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Peptide Receptors: 1159
        hemopexin receptor: 5

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 06/15/1988 - "Results of binding studies using mouse hepatoma cells and isolated domains indicate that domain I not only binds heme but also plays a vital part in the hemopexin-receptor interaction. " 04/15/1988 - "Competitive inhibition and saturation studies demonstrate that FeTPPS-hemopexin binds to the hemopexin receptor on mouse hepatoma cells but with a lower affinity (Kd 125 nM) more characteristic of apo-hemopexin than heme-hemopexin (Kd 65 nM). " 06/01/1991 - "Haemopexin receptors from mouse hepatoma (Hepa) cells were affinity-labelled by cross-linking to haem-125I-haemopexin complexes using two homo-[disuccinimidyl suberate (DSS) and 3,3'-dithiobis(succinimidyl propionate) (DTSSP)] and one hetero-[sulphosuccinimidyl 4-(p-maleimidophenyl)butyrate (sulpho-SMPB)] bifunctional cross-linking agents. " 06/15/1988 - "Importantly, SnPP-hemopexin binds to the hemopexin receptor on mouse hepatoma cells with an affinity comparable to that of heme-hemopexin and treatment of the hepatoma cells with SnPP-hemopexin causes a rapid increase in the steady state level of heme oxygenase messenger RNA. "
2.	Leukemia 06/25/1987 - "Immunoinhibition experiments using the antibody against the placental receptor revealed inhibition of binding of 125I-hemopexin to human leukemia K562 and HL 60 cells, thereby strongly supporting that the polypeptide isolated from the human placenta was the hemopexin receptor."

Related Drugs and Biologics

1.	Heme (Haem)
2.	Hemopexin
3.	Messenger RNA (mRNA)
4.	Peptides (Polypeptides)
5.	Heme Oxygenase (Decyclizing) (Heme Oxygenase)
6.	succinimidyl 4-(4-maleimidophenyl)butyrate
7.	3,3'-dithiobis(sulfosuccinimidyl propionate)
8.	disuccinimidyl suberate
9.	dithiobis(succinimidylpropionate)