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5-S-cysteinyldopamine

Also Known As:

5-SCDA; L-Cysteine, S-(5-(2-aminoethyl)-2,3-dihydroxyphenyl)-

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Catecholamines: 15682
    - Dopamine: 23033
      - 5-S-cysteinyldopamine: 6
  - Biogenic Amines: 992
    - Biogenic Monoamines: 29
      - Dopamine: 23033
        5-S-cysteinyldopamine: 6
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Catechols: 121
        Catecholamines: 15682
        Dopamine: 23033
        5-S-cysteinyldopamine: 6

Experts

1.	Montine, T J: 2 articles (12/2001 - 11/2001)
2.	Sidell, K R: 2 articles (12/2001 - 11/2001)
3.	Aureli, Cristina: 1 article (03/2014)
4.	Cassano, Tommaso: 1 article (03/2014)
5.	Chichiarelli, Silvia: 1 article (03/2014)
6.	Cocciolo, Annalisa: 1 article (03/2014)
7.	Fontana, Mario: 1 article (03/2014)
8.	Francioso, Antonio: 1 article (03/2014)
9.	Gaetani, Silvana: 1 article (03/2014)
10.	Mancini, Patrizia: 1 article (03/2014)

Related Diseases

1.	Parkinson Disease (Parkinson's Disease) 03/01/2014 - "5-S-cysteinyldopamine neurotoxicity: Influence on the expression of α-synuclein and ERp57 in cellular and animal models of Parkinson's disease." 01/01/2000 - "A characteristic change in the substantia nigra of Parkinson's disease patients is an apparent accelerated rate of dopamine oxidation as evidenced by an increased 5-S-cysteinyldopamine (5-S-CyS-DA) to dopamine ratio. " 01/01/2000 - "Oxidative metabolites of 5-S-cysteinyldopamine inhibit the alpha-ketoglutarate dehydrogenase complex: possible relevance to the pathogenesis of Parkinson's disease." 12/01/2001 - "Recent results from in vitro and in vivo models have suggested that some products from mercapturic acid pathway (MAP) metabolism of oxidized dopamine (DA) may contribute to dopaminergic neurodegeneration, and that at least one product of this pathway, 5-S-cysteinyldopamine (Cys-DA), is elevated in patients with advanced Parkinson's disease (PD). " 01/01/1996 - "High-performance liquid chromatography with electrochemical detection has been employed to analyze ultrafiltrates of cerebrospinal fluid of Parkinson's Disease (PD) patients and age-matched controls for the dopamine (DA) metabolites homovanillic acid (HVA) and 5-S-cysteinyldopamine (5-S-CyS-DA). "
2.	Ascorbic Acid Deficiency (Vitamin C Deficiency) 02/01/1991 - "Vitamin C deficiency facilitates 5-S-cysteinyldopamine formation in guinea pig striatum."

Related Drugs and Biologics

1.	Dopamine (Intropin)
2.	Acetylcysteine (Siran)
3.	Synucleins
4.	Levodopa (L Dopa)
5.	Ketoglutarate Dehydrogenase Complex (Oxoglutarate Dehydrogenase)
6.	Homovanillic Acid