misoprostol acid

de-esterified metabolite of misoprostol

Also Known As:

15-deoxy-16-hydroxy-16-methylprostaglandin E1; SC 30695; SC-30695; Prost-13-en-1-oic acid, 11,16-dihydroxy-16-methyl-9-oxo-, (11alpha,13E)-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Renal Insufficiency (Renal Failure) 02/01/1990 - "Finally, although values for some pharmacokinetic variables--maximum concentration of misoprostol acid, area under the concentration-time curve and elimination half-life--were increased in patients with renal failure compared with controls, these alterations do not warrant changes in misoprostol dosage. "
2.	Chronic Kidney Failure (Chronic Renal Failure) 04/01/1995 - "The dose of misoprostol may need to be reduced in ESRD patients on prolonged hemodialysis to prevent unnecessary high plasma levels of misoprostol acid and to avoid possible dose-related adverse effects."

1.	Misoprostol (Cytotec)

1.	Renal Dialysis (Hemodialysis)