desacetyluvaricin

isolated from Uvaria accuminata; structure given in first source

Networked: 3 relevant articles (0 outcomes, 2 trials/studies)

1.	Colorectal Neoplasms (Colorectal Cancer) 03/01/2014 - "In the present study, we found desacetyluvaricin (Dau) exhibited notable in vitro antiproliferative effect on SW480 human colorectal carcinoma cells with IC50 value of 14 nM. " 03/01/2014 - "Desacetyluvaricin induces S phase arrest in SW480 colorectal cancer cells through superoxide overproduction."
2.	Hepatocellular Carcinoma (Hepatoma) 07/01/2012 - "To investigate the anticancer effects of desacetyluvaricin (DES) on hepatocellular carcinoma (HCC) in vitro, and to study its mechanism. " 07/01/2012 - "The suppression effects of desacetyluvaricin on hepatocellular carcinoma and its possible mechanism."
3.	Lung Neoplasms (Lung Cancer) 05/01/2016 - "10 kinds of annonaceous acetogenins were selected for antitumor activity testing against human lung cancer cell line A549/Taxol and the structure activity relationship was analyzed.MTT assay was used to detect the inhibitory activities of 10 kinds of annonaceous acetogenins and positive drugs against A549/Taxol cells, respectively uvariamicin-Ⅲ(1), uvariamicin-Ⅱ(2), annosquacin D(3), desacetyluvaricin(4), annosquatin A(5), squamostatin D(6), bullatacin(7), squamocin(8), motrilin(9), annosquatin B(10), verapamil and cisplatin. "