mefloquine-sulfadoxine-pyrimethamine

combination of mefloquine, sulfadoxine, pyrimethamine

Also Known As:

Benzenesulfonamide, 4-amino-N-(5,6-dimethoxy-4-pyrimidinyl)-, mixt. with 5-(4-chlorophenyl)-6-ethyl-2,4-pyrimidinediamine and (R*,S*)-(+-)-alpha-2-piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol monohydrochloride; Fansimef; MSP 4

Networked: 41 relevant articles (7 outcomes, 11 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Badarin, Kathryn: 1 article (01/2021)
2.	Hemmingsson, Tomas: 1 article (01/2021)
3.	Hillert, Lena: 1 article (01/2021)
4.	Kjellberg, Katarina: 1 article (01/2021)
5.	Connolly, Mark P: 1 article (02/2017)
6.	Goodwin, Elizabeth: 1 article (02/2017)
7.	Schey, Carina: 1 article (02/2017)
8.	Zummo, Jacqueline: 1 article (02/2017)
9.	Burger, Renée J: 1 article (02/2016)
10.	Grobusch, Martin P: 1 article (02/2016)

Related Diseases

1.	Malaria 07/01/1990 - "[The efficacy of and tolerance for fansimef in the treatment of tropical malaria in the south of the Socialist Republic of Vietnam]." 12/01/1992 - "Fansimef for prophylaxis of malaria: a double-blind randomized placebo controlled trial." 11/01/1989 - "Chemosuppression of malaria by the triple combination mefloquine/sulfadoxine/pyrimethamine: a field trial in an endemic area in Malaysia." 11/01/1995 - "Mefloquine/sulfadoxine/pyrimethamine for malaria." 01/22/1991 - "Fansimef has also been under investigations for malaria. "
2.	Falciparum Malaria (Plasmodium falciparum Malaria) 12/01/1992 - "Eight episodes of symptomatic falciparum malaria occurred during the trial, seven in the placebo group, and one in the Fansimef group. " 01/01/1988 - "Double-blind dose finding study of mefloquine-sulfadoxine-pyrimethamine in children with acute falciparum malaria." 09/01/1995 - "Minimal effective dose of mefloquine/sulfadoxine/pyrimethamine in mild Plasmodium falciparum malaria." 01/01/1988 - "An attack of acute Plasmodium falciparum malaria occurred in one volunteer 6 weeks after discontinuation of prophylaxis with Fansimef. " 01/01/1987 - "From July 1985 until December 1986 a total of 5192 patients with falciparum malaria (1734 males, 3458 females) from this area were given supervised treatment with the combination mefloquine-sulfadoxine-pyrimethamine (MSP). "
3.	Parasitemia 12/01/1995 - "Background: The objectives of this study were (1) to compare the efficacy of Lariam (mefloquine) with that of Fansimef (mefloquine, sulfadoxine, and pyrimethamine), Fansidar (sulfadoxine and pyrimethamine), chloroquine, and placebo in suppressing asexual parasitemia in semi-immune persons living in an area endemic for Plasmodium falciparum malaria; and (2) to compare the tolerance of these drugs when taken over a prolonged period of time. "
4.	Infections 01/01/1990 - "falciparum cases treated for 10 d with quinine+tetracycline (QT) cleared the infection as often as those given one dose of mefloquine+sulfadoxine+pyrimethamine (MSP); both treatments reduced densities in cases not cured. " 09/01/1990 - "Phase III double-blind comparative study of Fansimef and Lariam for the curative treatment of Plasmodium falciparum infections in Thailand." 07/01/1999 - "Efficacy and tolerability of a low-dose mefloquine-sulfadoxine-pyrimethamine combination compared with chloroquine in the treatment of acute malaria infection in a population with multiple drug-resistant Plasmodium falciparum."
5.	Fever (Fevers) 01/01/1987 - "The rate of clearance of fever was marginally faster in the Fansimef group. " 05/01/1995 - "Mefloquine alone and mefloquine/sulfadoxine/pyrimethamine showed similar response rates and both reduced parasitaemia and fever more rapidly than chloroquine. "

Related Drugs and Biologics

1.	Mefloquine (Lariam)
2.	pyrimethamine drug combination fanasil (Fansidar)
3.	Chloroquine (Aralen)
4.	Pyrimethamine (Daraprim)
5.	Sulfadoxine (Sulformethoxine)
6.	Atovaquone (Mepron)
7.	Proguanil (Paludrine)
8.	Amodiaquine (Camoquin)
9.	Lumefantrine
10.	Artesunate

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Therapeutics
3.	Chemoprevention
4.	Bed Rest (Bedrest)