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bis(salicylaldoximato)copper(II)
Also Known As:
CuSAO2; trans-bis(salicylaldoximato)copper(II) complex
Networked:
3
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Organometallic Compounds: 64
bis(salicylaldoximato)copper(II): 3
Experts
1.
Elo, Hannu
: 1 article (11/2004)
Related Diseases
1.
Leukemia L1210
09/01/1985 - "
No activity against leukemia L1210 was found in female DBA/2J mice, although CuSAO2 is equally effective against L1210 and Ehrlich carcinoma cells in vitro.
"
11/01/2004 - "
The present results on human tumor cell lines are in line with previous observations that CuSAO2 and CuRES2 essentially totally inhibit the proliferation of leukemia L1210 and Ehrlich ascites carcinoma cells in vitro in a concentration as low as approximately 5 microg/ml.
"
09/01/1986 - "
Several derivatives and analogs of the recently reported antiproliferative and antitumor agent trans-bis(salicylaldoximato)copper(II) (CuSAO2) have been prepared and tested for antiproliferative activity against L1210 leukemia cells in vitro.
"
2.
Carcinoma (Carcinomatosis)
09/01/1985 - "
No activity against leukemia L1210 was found in female DBA/2J mice, although CuSAO2 is equally effective against L1210 and Ehrlich carcinoma cells in vitro.
"
11/01/2004 - "
The present results on human tumor cell lines are in line with previous observations that CuSAO2 and CuRES2 essentially totally inhibit the proliferation of leukemia L1210 and Ehrlich ascites carcinoma cells in vitro in a concentration as low as approximately 5 microg/ml.
"
11/01/2004 - "
The copper chelate trans-bis(salicylaldoximato)copper(II), CuSAO2, is a powerful antitumor agent in vivo, being capable of drastically increasing the life span of mice bearing Ehrlich ascites carcinoma, and has in many cases even a curative effect.
"
3.
Weight Loss (Weight Reduction)
09/01/1985 - "
The side effects of CuSAO2 included weight loss, weakness, acrodynia, and blindness; all of these side effects were transient.
"
4.
Melanoma (Melanoma, Malignant)
11/01/2004 - "
The results obtained for the melanomas are of special interest, since CuRES2 (and even more so CuSAO2) have very low aqueous solubilities.
"
5.
Blindness (Hysterical Blindness)
09/01/1985 - "
The side effects of CuSAO2 included weight loss, weakness, acrodynia, and blindness; all of these side effects were transient.
"
Related Drugs and Biologics
1.
bis(salicylaldoximato)copper(II)
2.
Antineoplastic Agents (Antineoplastics)
3.
Copper