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macrophage-derived immunosuppressor factor
from human monocytic cell line THP-1; inhibits production & action of interleukin 2; MW 60,000-70,000; sensitive to trypsin, chymotrypsin & protease
Also Known As:
MDSF; macrophage-derived suppressor factor
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
macrophage-derived immunosuppressor factor: 3
Experts
1.
Mathew, Manish J
: 1 article (01/2017)
2.
Pruthi, Nupur
: 1 article (01/2017)
3.
Rao, Malla B
: 1 article (01/2017)
4.
Savardekar, Amey R
: 1 article (01/2017)
5.
Tiwari, Sarbesh
: 1 article (01/2017)
Related Diseases
1.
Thrombosis (Thrombus)
01/01/2017 - "
MDSF can present with quadriparesis/quadriplegia due to middle one-third SSS obstruction/thrombosis leading to bilateral motor cortical venous infarction.
"
2.
Quadriplegia (Spastic Quadriplegia)
01/01/2017 - "
MDSF can present with quadriparesis/quadriplegia due to middle one-third SSS obstruction/thrombosis leading to bilateral motor cortical venous infarction.
"
3.
Pancreatic Fistula (Pancreatic Fistulas)
05/01/2023 - "
Since the possibility of developing pancreatic fistula is high in cases with MDSF ≥16 mm, careful surgical strategies, such as having a skilled physician, are necessary.
"
05/01/2023 - "
Among the subcutaneous fat lengths, the MDSF was the most useful, and the optimal cut-off value was 16 mm. MDSF and non-expert surgeons were found to be independent risk factors for pancreatic fistula.
"
4.
Leukemia
11/01/1989 - "
When 130- to 150-kDa fractions from Sephadex G200 of the M phi and EC supernatants were treated with an antibody against a macrophage-derived suppressor factor produced by the human monocytic leukemia cell line THP-1, the activity of both fractions was neutralized.
"
5.
Infarction (Infarctions)
01/01/2017 - "
MDSF can present with quadriparesis/quadriplegia due to middle one-third SSS obstruction/thrombosis leading to bilateral motor cortical venous infarction.
"
Related Drugs and Biologics
1.
sephadex