sialate O-acetylesterase

rat liver cytosol non-glycosylated enzyme has an active-site serine; rat liver membrane associated glycosylated enzyme is specific for 9-O-acetylated sialic acids

Also Known As:

9-O-acetylestrase; 9-O-acetylsialic acid esterase; influenza C virus receptor destroying enzyme; neuraminate-O-acetylesterase; sialic acid acetylesterase, human; sialic acid acetylesterase, mouse

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Carboxylic Ester Hydrolases: 62
        Acetylesterase: 110
        sialate O-acetylesterase: 2

Experts

1.	Baric, Ralph S: 1 article (07/2015)
2.	Dong, Wenjuan: 1 article (07/2015)
3.	Golda, Anna: 1 article (07/2015)
4.	Huang, Xingchuan: 1 article (07/2015)
5.	Li, Wenhui: 1 article (07/2015)
6.	Marasco, Wayne A: 1 article (07/2015)
7.	Milewska, Aleksandra: 1 article (07/2015)
8.	Pyrc, Krzysztof: 1 article (07/2015)
9.	Qi, Yonghe: 1 article (07/2015)
10.	Sims, Amy C: 1 article (07/2015)

Related Diseases

1.	Infections 07/01/2015 - "These results demonstrate that hCoV-HKU1 exploits O-Ac-Sia as a cellular attachment receptor determinant to initiate the infection of host cells and that its HE protein possesses the corresponding sialate-O-acetylesterase RDE activity. " 07/01/2015 - "This is the first study to demonstrate that hCoV-HKU1 uses certain types of O-acetylated sialic acid residues on glycoproteins to initiate the infection of host cells and that the HKU1-HE protein possesses sialate-O-acetylesterase RDE activity."
2.	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/01/2012 - "Regulation of O-acetylation of sialic acids by sialate-O-acetyltransferase and sialate-O-acetylesterase activities in childhood acute lymphoblastic leukemia."

Related Drugs and Biologics

1.	N-Acetylneuraminic Acid (Sialic Acid)
2.	Proteins (Proteins, Gene)
3.	Glycoproteins (Glycoprotein)
4.	Sialic Acids
5.	Acetyltransferases