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pyroglutamyl diazomethyl ketone

structure given in first source

Also Known As:

PGDMK

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - Pyrrolidinones: 162
      - Pyrrolidonecarboxylic Acid: 255
        pyroglutamyl diazomethyl ketone: 1
Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Acidic Amino Acids: 44
    - Glutamates: 45
      - Pyrrolidonecarboxylic Acid: 255
        pyroglutamyl diazomethyl ketone: 1
  - Cyclic Amino Acids: 3
    - Imino Acids: 11
      - Pyrrolidonecarboxylic Acid: 255
        pyroglutamyl diazomethyl ketone: 1

Experts

1.	Abe, Koji: 1 article (03/2006)
2.	Bulau, Patrick: 1 article (03/2006)
3.	Morty, Rory E: 1 article (03/2006)
4.	Pellé, Roger: 1 article (03/2006)
5.	Wilk, Sherwin: 1 article (03/2006)

Related Diseases

1.

African Trypanosomiasis (Nagana)

03/15/2006 - "Employing an activity-neutralizing anti-trypanosome PGP antibody, and pyroglutamyl diazomethyl ketone, a specific inhibitor of type I PGP, we demonstrated that trypanosome PGP is entirely responsible for the reduced plasma half-life of TRH, and partially responsible for the reduced plasma half-life of GnRH in a rodent model of African trypanosomiasis. "

Related Drugs and Biologics

1.	Gonadotropin-Releasing Hormone (GnRH)