3- (2- (4- azidobenzamidino)ethyl)- 5- hydroxyindole (SABA)

structure given in first source
Also Known As:
SABA; serotonin azidobenzamidine
Networked: 166 relevant articles (16 outcomes, 31 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Schatz, Michael: 8 articles (11/2014 - 05/2010)
2. Zeiger, Robert S: 6 articles (11/2014 - 05/2010)
3. Chen, Wansu: 5 articles (11/2014 - 05/2010)
4. Stanford, Richard H: 5 articles (01/2014 - 07/2004)
5. Blais, Lucie: 5 articles (01/2014 - 03/2007)
6. Navaratnam, Prakash: 5 articles (05/2011 - 12/2009)
7. Gutierrez, Benjamin: 5 articles (01/2011 - 09/2009)
8. Ducharme, Francine M: 4 articles (10/2015 - 01/2009)
9. Postma, Dirkje S: 4 articles (01/2015 - 06/2005)
10. Forget, Amélie: 4 articles (11/2011 - 03/2007)

Related Diseases

1. Asthma (Bronchial Asthma)
05/01/2010 - "The number of SABA canisters dispensed is most strongly related to improved asthma outcomes, followed by the unweighted medication ratio; dispensing of any controller is least related. "
01/01/2010 - "The objectives are: (1) To assess diagnostic test characteristics of six alternative index tests compared with the selected reference standard-a standardized exercise challenge test (ECT) in patients with suspected exercise-induced bronchoconstriction or asthma (EIB/EIA); (2) to determine the efficacy of a single prophylactic dose of four pharmacologic and one nonpharmacologic interventions vs. placebo to attenuate EIB/EIA in patients with diagnosed EIB/EIA; and (3) to determine if regular daily treatment with short-acting or long-acting beta-agonists (SABA or LABA) causes patients with EIA to develop tachyphylaxis when additional prophylactic doses are used pre-exercise. "
01/01/2014 - "Patients with one or more claims with asthma diagnosis, two or more prescriptions for FSC (250/50- or 100/50-mg formulations) or FP (220- or 110-mg formulations), and one or more asthma exacerbations or five or more short-acting beta agonist (SABA) prescriptions within 1 year before initial receipt of study medications were included. "
12/01/2012 - "The study identified critical values of SABA use that predict future asthma events. "
11/01/2011 - "Our study supports the evidence of SABA safety during pregnancy, but more research is required to assess whether the increased risk of malformations among LABA users is due to the medication, bias by asthma severity, or chance alone."
2. Chronic Obstructive Pulmonary Disease (COPD)
3. Hyperventilation
01/01/2007 - "Furthermore, SABA significantly inhibited the decrease in IC due to hyperventilation. "
01/01/2007 - "These findings suggest that lung hyperinflation following hyperventilation may be a useful method for detecting dynamic hyperinflation observed not only in patients with COPD but also in ex-smokers without COPD, and both SAAC and SABA are effective in reducing dynamic hyperinflation in COPD."
01/01/2007 - "Fifty-nine patients with COPD, 20 ex-smokers without COPD and 20 healthy subjects who had never smoked were examined for dynamic hyperinflation by metronome-paced hyperventilation with respiratory rate increasing from 20 to 30 and 40 tidal breaths/min. Dynamic hyperinflation was evaluated as the decrease in inspiratory capacity (IC) following hyperventilation, and the effects of SAAC and SABA on dynamic hyperinflation were assessed. "
01/01/2007 - "The present study was performed to examine the occurrence of dynamic hyperinflation following hyperventilation in COPD patients and former smokers without COPD, and the efficacy of short-acting anticholinergic agents (SAAC) and beta2-agonists (SABA) for lung hyperinflation following metronome-paced hyperventilation in COPD. "
03/01/2013 - "Thirty-two patients with stable COPD who had been treated with long-acting bronchodilators, including long-acting muscarinic antagonists (LAMA), were examined by pulmonary function tests, dynamic hyperinflation evaluated by the method of step-wise metronome-paced incremental hyperventilation, and the incremental shuttle walking test before and after inhalation of SABA or SAMA. "
4. Cough
5. Prostatic Hyperplasia (Benign Prostatic Hyperplasia)

Related Drugs and Biologics

1. Adrenal Cortex Hormones (Corticosteroids)
2. salmeterol (Serevent)
3. formoterol (Oxis)
4. Cholinergic Antagonists (Anticholinergics)
5. fluticasone (Cutivate)
6. Bronchodilator Agents (Bronchodilators)
7. Albuterol (Salbutamol)
8. Muscarinic Antagonists
9. N- ((2,3- dihydro- 1,4- benzodioxin- 2- yl)methyl)- 5- methoxy- 1H- indole- 3- ethanamine
10. montelukast (Singulair)

Related Therapies and Procedures

1. Nebulizers and Vaporizers (Inhaler)
2. Metered Dose Inhalers (Metered Dose Inhaler)
3. Dry Powder Inhalers
4. Home Nursing (Nursing, Home)
5. Ambulatory Care (Outpatient Care)