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mitosene

structure given in first source

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Quinones: 434
  - Indolequinones: 12
    - Mitomycins: 11
      - mitosene: 4
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azirines
    - Mitomycins: 11
      - mitosene: 4
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indolequinones: 12
        Mitomycins: 11
        mitosene: 4

Experts

1.	Champeil, Elise: 1 article (04/2016)
2.	Cheng, Shu-Yuan: 1 article (04/2016)
3.	Conchero-Guisan, Marta: 1 article (04/2016)
4.	Huang, Bik Tzu: 1 article (04/2016)
5.	Martinez, Thibaut: 1 article (04/2016)
6.	Paz, Manuel M: 1 article (04/2016)
7.	Sapse, Anne-Marie: 1 article (04/2016)
8.	Bargonetti, Jill: 1 article (07/2010)
9.	Bhosle, Rahul C: 1 article (07/2010)
10.	Boamah, Ernest K: 1 article (07/2010)

Related Diseases

1.	Neoplasms (Cancer) 07/19/2010 - "We find the increase in mitosene 1-beta-adduct formation correlates with a condensed nuclear morphology and increased cytotoxicity in human cancer cells with or without p53. " 07/01/1989 - "Surprisingly, the in vivo activities of mitosene diol 8b and mitosene diacetate 10b against the gastric human tumor xenograft GXF 97 were very high and comparable with that of mitomycin C." 04/01/2016 - "The major monoadducts generated by MC and DMC in tumor cells have opposite stereochemistry at carbon one of the guanine-mitosene bond: trans (or alpha) for MC and cis (or beta) for DMC. "
2.	Leukemia P388 10/01/1981 - "A series of 1-substituted mitosene analogues of the mitomycin antitumor antibiotics was prepared by total synthesis and screened for activity against P388 leukemia in mice. "

Related Drugs and Biologics

1.	Mitomycin (Mitomycin-C)
2.	Guanine
3.	Carbon
4.	Anti-Bacterial Agents (Antibiotics)