eticlopride

blocks dopamine-D2 binding sites; structure given in first source; RN given refers to (S)-isomer

Also Known As:

5-chloro-3-ethyl-N-((1-ethyl-2-pyrrolidinyl)methyl)-6-methoxysalicylamide; A 38503; FLB 131; FLB-131

Networked: 25 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Salicylamides: 2
    - eticlopride: 25

Experts

1.	Cahill, Catherine M: 1 article (01/2022)
2.	Grenier, Patrick: 1 article (01/2022)
3.	Mailhiot, Madison C: 1 article (01/2022)
4.	Olmstead, Mary C: 1 article (01/2022)
5.	Ferrari, Luiz F: 1 article (01/2021)
6.	Gianlorenço, Anna Carolyna L: 1 article (01/2021)
7.	Guilherme, Evelyn M: 1 article (01/2021)
8.	Pei, JunZhu: 1 article (01/2021)
9.	Ramirez, Anna: 1 article (01/2021)
10.	Rey, Charles: 1 article (01/2021)

Related Diseases

1.	Shock 01/01/2021 - "In addition, the administration of Dopamine and SCH-233390 had no effects on emotional memory acquisition, but the animals that received the highest dose of Eticlopride had an improvement in aversive memory acquisition, shown by a suppression of its innate preference for the dark compartment of the inhibitory avoidance apparatus following an exposure to a foot shock. " 06/01/1993 - "In squirrel monkeys responding under a fixed-ratio schedule of stimulus-shock termination, the effects of (+)-PHNO were determined alone and in combination with the selective D2 antagonist eticlopride, the selective D1 antagonist (-)-trans-6,7,7a,8,9,13b- hexahydro-3-chloro-2-hydroxy-N-methyl-5H-benzo(d)naphtho-(2,1)azepine (SCH 39166), the nonselective D1/D2 antagonist cis-flupentixol or the atypical neuroleptic clozapine. "
2.	Amnesia (Dissociative Amnesia) 01/01/2014 - "One-dose methamphetamine treatment (i.p., 30 min before or immediately after the training trial) induced hyperlocomotion and amnesia in mice, which were blocked by eticlopride but not by baicalein pretreatment. "
3.	Vomiting 04/22/1996 - "Intracerebroventricularly administered S(-)-eticlopride (0.01-1 microgram) also inhibited the emesis induced by s.c. " 11/23/2001 - "S(-)-eticlopride (10 microg/kg, i.c.v.) did not inhibit emesis induced by cisplatin. " 04/22/1996 - "S(-)-Eticlopride, which has a high affinity for the dopamine D3 receptor, antagonized R(+)-7-OH-DPAT (0.3 mg/kg, s.c.)-induced emesis (ID50 1.4 micrograms/kg, s.c.). " 01/01/1995 - "The emesis induced by R(+)-7-OH-DPAT (0.3 mg/kg, s.c.) was inhibited by S(-)-eticlopride (0.01-0.1 mg/kg, s.c.), a potent D2 and D3 receptor antagonist but not by SCH-23390 (1 mg/kg, s.c.), a selective D1 receptor antagonist or clozapine (1 mg/kg, s.c.), a D4 receptor antagonist. "
4.	Photophobia (Light Sensitivity) 12/01/2016 - "In the P23H rat model of retinitis pigmentosa, the dopamine D2 receptor antagonists sulpiride and eticlopride appear to improve visual responses of retinal ganglion cells (RGCs) by increasing light sensitivity of RGCs and transforming abnormal, long-latency ON-center RGCs into OFF-center cells. " 01/01/2015 - "The dopamine D2/D3 receptor antagonists sulpiride and eticlopride and the D4 receptor antagonist L-745,870 increased light sensitivity of P23H rat RGCs but decreased light sensitivity in Sprague-Dawley rat RGCs. "
5.	Pain (Aches) 04/01/2001 - "Neither naltrexone nor eticlopride affected formalin pain scores. " 06/01/2007 - "Attenuation of pain-related responses induced by striatal administration of quinpirole was reversed by intrathecal administration of a dopamine D(2) receptor antagonist (eticlopride) or a non-selective 5-HT receptor antagonist (methysergide), but not by an alpha(2)-adrenoceptor antagonist (atipamezole). "

Related Drugs and Biologics

1.	Dopamine (Intropin)
2.	Methamphetamine (Desoxyn)
3.	P-30 composite resin (P 30)
4.	baicalein
5.	SCH 23390
6.	Sulpiride (neogama)
7.	Dopamine D2 Receptor Antagonists
8.	Dopamine D3 Receptors
9.	Quinpirole
10.	Haloperidol (Haldol)