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2- (4- (3- methyl- 2- butenyl)phenyl)propionic acid

PGE antagonist

Also Known As:

TA 60; TA-60; Benzeneacetic acid, alpha-methyl-4-(3-methyl-2-butenyl)-

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phenylpropionates
      - 2-(4-(3-methyl-2-butenyl)phenyl)propionic acid: 7

Experts

1.	Hlusko, Katelyn C: 1 article (05/2022)
2.	Hofmeister, Erik: 1 article (05/2022)
3.	Linden, Daniel S: 1 article (05/2022)
4.	Matz, Brad M: 1 article (05/2022)
5.	Tillson, D Michael: 1 article (05/2022)
6.	Nawata, H: 1 article (10/2003)
7.	Nishiyama, K-I: 1 article (10/2003)
8.	Takata, M: 1 article (10/2003)
9.	Tsuneyoshi, M: 1 article (10/2003)
10.	Yao, T: 1 article (10/2003)

Related Diseases

1.	Body Weight (Weight, Body) 05/01/2022 - "The mean ± standard deviation body weights across the groups were 18.7 ± 6.1 kg, 16.2 ± 7.5 kg, and 14.2 ± 5.5 kg for the TA 30 V3 2.5 mm, TA 60 3.5 mm, and TA 60 4.8 mm groups, respectively (P = .48). " 04/01/1995 - "Dose of AE (100), TA (60) and AB (30) mg., equivalent of the plant material per kg. Body weight of the extracts were administered orally to the female albino rats. "
2.	Ulcer 01/01/1985 - "Effect of a new anti-inflammatory drug which has a little ulcer inducing property on gastrointestinal tract, TA-60 (2-[4-(3-methyl-2-butenyl) phenyl] propionic acid), on the prostaglandin (PG) metabolism was investigated. "
3.	Necrosis 12/01/1985 - "TA-60 showed a protective effect against gastric necrosis induced by necrotizing agents such as HCl, NaOH or NaOH + EtOH. "
4.	Erythema 12/01/1985 - "TA-668 and TA-60 as well as other ANSAIDs inhibited the arachidonic acid (AA)-induced erythema, but did not inhibit the PGE2-induced erythema. "
5.	Diarrhea 12/01/1985 - "TA-60 showed about a 4 times less potent activity than ibuprofen in delay of occurring time of castor oil-induced diarrhea in rats. "

Related Drugs and Biologics

1.	Arachidonic Acid (Vitamin F)
2.	Prostaglandins
3.	Ibuprofen (Motrin)
4.	Castor Oil (Oil, Castor)
5.	2-(4-(2,2-dichlorovinyl)phenyl)propionic acid
6.	propionic acid (potassium propionate)