N-(4,4-diphenyl-3-butenyl)nipecotic acid

structure given in first source

Also Known As:

N-(4,4-diphenyl-3-butenyl)homo-beta-proline; N-(4,4-diphenyl-3-butenyl)piperidine-3-carboxylic acid; SK&F 100561; SK&F 89976; SK&F 89976-A; SK&F 89976-A, (+-)-isomer; SK&F 89976-A, (R)-isomer; SK&F 89976-A, hydrochloride; SK&F 89976-A, hydrochloride, (R)-isomer; SK&F 89976-A, hydrochloride, (S)-isomer; SK&F-100561; SKF 89976A

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - Nipecotic Acids
      - N-(4,4-diphenyl-3-butenyl)nipecotic acid: 2
- Heterocyclic Acids
  - Nipecotic Acids
    - N-(4,4-diphenyl-3-butenyl)nipecotic acid: 2

Related Diseases

Seizures (Absence Seizure)

07/01/1991 - "Like intraperitoneal (i.p.) PHT, CBZ, VPA, and CZP, SK&F 89976-A and SK&F 100330-A inhibited seizures in corneally kindled rats. "
01/01/1987 - "The ability of SK&F 89976-A and diazepam to inhibit the development of full amygdala kindled seizures may be related to enhancement of central inhibitory GABAergic systems."
01/01/1987 - "The prophylactic effect of an inhibitor of synaptosomal GABA uptake, SK&F 89976-A (N-[4,4-diphenyl-3-butenyl]-nipecotic acid), on the development of amygdala kindled seizures was studied in adult female rats. "

Related Drugs and Biologics

1.	gamma-Aminobutyric Acid (GABA)
2.	Diazepam (Valium)
3.	SK&F 100330-A
4.	nipecotic acid
5.	diphenyl (biphenyl)