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SK&F 100330-A
structure given in first source
Also Known As:
N-(4,4-diphenyl-3-butenyl)guvacine; SKF-100330A
Networked:
1
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyridines: 88
Nicotinic Acids: 13
SK&F 100330-A: 1
Heterocyclic Acids
Nicotinic Acids: 13
SK&F 100330-A: 1
Related Diseases
1.
Seizures (Absence Seizure)
07/01/1991 - "
SK&F 100330-A provided complete protection against picrotoxin-induced seizures (s.c.
"
07/01/1991 - "
Intraperitoneal SK&F 100330-A provided complete protection against pentylenetetrazol-induced seizures [subcutaneous (s.c.) PTZ] in mice but was ineffective against seizures induced by maximal electroshock (MES) at doses slightly greater than its TD50.
"
07/01/1991 - "
Like intraperitoneal (i.p.) PHT, CBZ, VPA, and CZP, SK&F 89976-A and SK&F 100330-A inhibited seizures in corneally kindled rats.
"
07/01/1991 - "
Pic) and against both clonus and forelimb tonic extension induced by NMDA N-methyl-D-aspartate [intracerebral ventricular (i.c.v.)-NMDA] in mice; however, SK&F 100330-A was ineffective against seizures induced by bicuculline (s.c.
"
Related Drugs and Biologics
1.
Picrotoxin
2.
Pentylenetetrazole (Metrazol)
3.
N-Methylaspartate (NMDA)
4.
Bicuculline
5.
N-(4,4-diphenyl-3-butenyl)nipecotic acid