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TEI 5103 (TG 51)
structure given in first source
Also Known As:
TG 51
; 3-(4-(trans-4-aminomethylcyclohexylcarbonyl)phenyl)propionic acid hydrochloride; TEI-5103; TG-51; Benzenepropanoic acid, 4-((4-(aminomethyl)cyclohexyl)carbonyl)-, hydrochloride, trans-
Networked:
9
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Carboxylic Acids: 973
Carbocyclic Acids
Phenylpropionates
TEI 5103: 9
Experts
1.
Ding, George X
: 1 article (09/2021)
Related Diseases
1.
Ulcer
01/01/1992 - "
A sensitive and specific radioimmunoassay for a new anti-ulcer drug TG-51 has been developed and applied to the evaluation of its pharmacokinetics in humans.
"
01/01/1992 - "
Development of radioimmunoassay for TG-51, a new anti-ulcer drug, and its application.
"
11/01/1987 - "
In conclusion, TEI-5103, when given orally, distributes in the gastric mucosa as a target issue directly from the lumen; and only the oral and gastric route of administration lead to the anti-ulcer effect.
"
11/01/1987 - "
These results suggest that the presence of TEI-5103 in the stomach is necessary to elicit its anti-ulcer effect.
"
11/01/1987 - "
The results indicate that TEI-5103 increases GMBF by acting directly on the gastric microcirculation and that this increasing effect may contribute to the anti-ulcer activity of TEI-5103.
"
2.
Prediabetic State (Prediabetes)
11/05/2022 - "
After adjustment for body mass index (BMI), triacylglycerol/high-density lipoprotein (TG/HDL) ratio and the presence of prediabetes, triacylglycerol (TG) 12:0_18:2_22:6, TG 16:0_11:1_18:2, TG 49:0, TG 51:1 and diacylglycerol (DG) 18:2_22:6 were independently associated with increased T2D risk, whereas lyso-phosphatidylcholine (LPC) O-16:0, LPC P-16:0, LPC O-18:0 and LPC 18:1 were independently associated with decreased T2D risk.
"
3.
Peptic Ulcer (Peptic Ulcers)
01/01/1985 - "
These results indicate that TEI-5103 is effective as an anti-ulcer agent increasing gastric mucosal blood flow and possibly promoting the healing process of peptic ulcers.
"
4.
Dementia (Dementias)
01/01/2022 - "
Notably, L-proline, L-cystine, ADMA, and N1-acetylspermidine were significantly changed in MCR-only, and PC(40:3), SM(32:1), TG(51:3), eicosanoic acid(20:1), methyl-D-galactoside and TG(50:3) contributed most to the prediction model for MCR-III. Pre-dementia syndrome of MCR has distinct metabolic subtypes, and SCCs and SG may cause different metabolic changes to develop MCR.
"
5.
Burns
09/01/2021 - "
For electron dosimetry, both the AAPM TG-51 and IAEA TRS-398 recommend the use of two formulas developed by Burns et al [Med. Phys.
"
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1.
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2.
Triglycerides (Triacylglycerol)
3.
Serotonin (5 Hydroxytryptamine)
4.
Prostaglandins
5.
Proline (L-Proline)
6.
Phosphatidylcholines (Phosphatidylcholine)
7.
HDL Lipoproteins
8.
Indomethacin (Indometacin)
9.
Diglycerides
10.
Cystine (L-Cystine)