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4-carboxyfluorescein

Also Known As:

4(5)-carboxyfluorescein; 5-carboxyfluorescein

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Spiro Compounds: 2
      - Fluoresceins: 2
        4-carboxyfluorescein: 5
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Xanthenes: 65
      - Fluoresceins: 2
        4-carboxyfluorescein: 5
Polycyclic Compounds: 6
- Spiro Compounds: 2
  - Fluoresceins: 2
    - 4-carboxyfluorescein: 5

Experts

1.	Cui, Ruixue: 1 article (03/2018)
2.	Gao, Xuechuan: 1 article (03/2018)
3.	Ji, Guanfeng: 1 article (03/2018)
4.	Liu, Zhiliang: 1 article (03/2018)
5.	Burwell, Timothy J: 1 article (10/2017)
6.	Connor, Jane: 1 article (10/2017)
7.	Huang, Yufeng: 1 article (10/2017)
8.	Hwang, Jeongmin: 1 article (10/2017)
9.	Li, Yang: 1 article (10/2017)
10.	Peterson, Norman C: 1 article (10/2017)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2017 - "This strategy not only should allow the creation of clustered 5-carboxyfluorescein (FAM)-fluorescence spots in response to human-telomerase activity in individual cancer cells but also could efficiently deliver drugs to reduce the undesired death of healthy cells. " 03/29/2018 - "After covalent grafting the targeting reagent folic acid (FA) and the fluorescence imaging agent 5-carboxyfluorescein (5-FAM), UIO-66-NH2-FA-5-FAM/5-FU can target the cancer cells HePG-2 and display excellent fluorescence imaging in vitro. " 03/03/2014 - "Both fluorescent imaging and flow cytometry measurements confirmed the effect of palmitoylation on the increased internalization of the Tat conjugates with either 5-carboxyfluorescein (5-FAM), a nonmembrane penetrating dye, or doxorubicin, an anticancer cancer drug that can readily diffuse across cell membranes. "
2.	Pulmonary Fibrosis (Fibrosing Alveolitis) 10/24/2017 - "Here, we show that a designed peptide (collagen hybridizing peptide: CHP), which specifically hybridizes to the degraded, unfolded collagen chains, can be used to image degraded collagen and inform tissue remodeling activity in various tissues: labeled with 5-carboxyfluorescein and biotin, CHPs enabled direct localization and quantification of collagen degradation in isolated tissues within pathologic states ranging from osteoarthritis and myocardial infarction to glomerulonephritis and pulmonary fibrosis, as well as in normal tissues during developmental programs associated with embryonic bone formation and skin aging. "
3.	Prostatic Neoplasms (Prostate Cancer) 01/01/2013 - "Two of the peptide sequences deduced from DNA sequencing of binding phages, SHSFSVGSGDHSPFT and GRFLTGGTGRLLRIS were labeled with 5-carboxyfluorescein and shown to bind and co-internalize with PSMA on human prostate cancer cells by fluorescence microscopy. "
4.	Osteoarthritis 10/24/2017 - "Here, we show that a designed peptide (collagen hybridizing peptide: CHP), which specifically hybridizes to the degraded, unfolded collagen chains, can be used to image degraded collagen and inform tissue remodeling activity in various tissues: labeled with 5-carboxyfluorescein and biotin, CHPs enabled direct localization and quantification of collagen degradation in isolated tissues within pathologic states ranging from osteoarthritis and myocardial infarction to glomerulonephritis and pulmonary fibrosis, as well as in normal tissues during developmental programs associated with embryonic bone formation and skin aging. "
5.	Myocardial Infarction 10/24/2017 - "Here, we show that a designed peptide (collagen hybridizing peptide: CHP), which specifically hybridizes to the degraded, unfolded collagen chains, can be used to image degraded collagen and inform tissue remodeling activity in various tissues: labeled with 5-carboxyfluorescein and biotin, CHPs enabled direct localization and quantification of collagen degradation in isolated tissues within pathologic states ranging from osteoarthritis and myocardial infarction to glomerulonephritis and pulmonary fibrosis, as well as in normal tissues during developmental programs associated with embryonic bone formation and skin aging. "

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