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1-nitrosopyrene

structure given in first source

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Pyrenes: 10
        1-nitrosopyrene: 4
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Pyrenes: 10
    - 1-nitrosopyrene: 4

Related Diseases

1.	Neoplasms (Cancer) 07/01/1988 - "This study was carried out in order to evaluate possible mechanisms responsible for tumor induction by 1-nitropyrene and to provide insights on the higher tumorigenicity of 1-nitrosopyrene than 1-nitropyrene in newborn mouse liver. " 08/01/1986 - "The presumed proximate carcinogen, 1-nitrosopyrene, administered at 700 nmol per mouse, caused liver tumors in 45% of the males and in 9% of the females. "
2.	Xeroderma Pigmentosum (Kaposi's Disease) 03/01/1988 - "The cytotoxic effects of 1-nitropyrene and 1-nitrosopyrene were compared in fibroblasts from normal persons, from excision-repair-deficient xeroderma pigmentosum (XP) patients, and from a patient with an inherited predisposition to malignant melanoma of the skin (hereditary cutaneous malignant melanoma [HCMM]). "
3.	Melanoma (Melanoma, Malignant) 03/01/1988 - "The cytotoxic effects of 1-nitropyrene and 1-nitrosopyrene were compared in fibroblasts from normal persons, from excision-repair-deficient xeroderma pigmentosum (XP) patients, and from a patient with an inherited predisposition to malignant melanoma of the skin (hereditary cutaneous malignant melanoma [HCMM]). "
4.	Adenocarcinoma 08/01/1988 - "Percentages of incidences of mammary adenocarcinomas in female rats were as follows: 1-nitropyrene, high dose (63%); 1-nitropyrene, low dose (42%); 1-nitrosopyrene (19%); 1-aminopyrene (4%) trioctanoin (3%). "
5.	Cutaneous Malignant Melanoma 03/01/1988 - "The cytotoxic effects of 1-nitropyrene and 1-nitrosopyrene were compared in fibroblasts from normal persons, from excision-repair-deficient xeroderma pigmentosum (XP) patients, and from a patient with an inherited predisposition to malignant melanoma of the skin (hereditary cutaneous malignant melanoma [HCMM]). "

Related Drugs and Biologics

1.	1-nitropyrene
2.	Carcinogens
3.	1-aminopyrene
4.	tricaprylin