Nocardia cell wall skeleton

04/15/1986 - "The effect of immunotherapy with Nocardia rubra cell-wall skeleton (N-CWS) on remission duration and survival of adults with acute myelogenous leukemia (AML) was studied in a prospective randomized controlled study. "
04/01/1986 - "The effect of immunotherapy with Nocardia rubra cell-wall skeleton (N-CWS) on the remission duration and survival of adults with acute myelogenous leukemia (AML) was studied in a prospective randomized controlled study. "

04/01/1979 - "Immune spleen cells obtained from +/+ mice after footpad inoculation of MCA tumor cells mixed with N-CWS were effective in suppressing the MCA tumor growth, although those obtained from mice after inoculation of MCA tumor cells mixed with BCG-CWS did not exhibit a suppressive effect. "
09/01/2019 - "Our study provides evidence that N-CWS could significantly increase the growth of CIK cells, DCs, and NK cells, particularly due to its robust antitumor activities by inducing apoptosis, and attenuate the invasion and migration of tumor cells."
01/01/1988 - "The present study elucidated that N-CWS augments the cytolytic activity against 3LL tumor cells of LAK cells from N-CWS-immunized mice administered i.p. "
09/01/2019 - "Finally, CIK/NK cells could notably suppress the invasion and migration of tumor cells in the presence of N-CWS. "
05/01/1996 - "After elimination of the influence of smoking level, a significant suppression of development of cancers was noted in the N-CWS-treated workers as compared to the untreated controls. "

03/01/1985 - "These results indicate the clinical effectiveness of the N-CWS treatment, especially in curatively resectable lung cancer. "
01/01/1984 - "These results indicate the clinical effectiveness of the N-CWS treatment especially in curatively resectable lung cancer. "
04/01/1983 - "These results indicate the clinical effectiveness of the N-CWS treatment especially in curatively resectable lung cancer. "
11/01/1983 - "In order to evaluate the clinical benefit of Nocardia rubra cell wall skeleton (N-CWS), a randomized controlled study was performed with inoperable lung cancer patients entered in 5 institutions from October 1978 to June 1981. "
01/01/1987 - "The cytostatic activity of pleural macrophages for human lung cancer cells (PC-9) was augmented following incubation of pleural mononuclear cells with 10 micrograms/ml N-CWS for 24 h. "

10/01/1989 - "This study documents that ADM treatment and intralesionally administered N-CWS are effective in the treatment of bovine leukosis."
12/01/1990 - "Fresh tumor infiltrated cells obtained from lymphatic nodule at 8 days after injection of N-CWS showed cytotoxic activity against bovine leukemia cell line, but this activity decreased with the time of cultivation and no activity could be detected after 14 days cultivation. "

01/01/1985 - "Combined treatment with N-CWS and CP after ENU treatment caused prolongation of the average survival period of rats and a statistically significant reduction in the incidence of leukemia. "
01/01/1985 - "Five administrations of N-CWS following ENU treatment caused a slight prolongation of the average survival of rats but did not reduce the incidence of leukemia. "
12/01/1983 - "No difference in NK cell activity against K-562 derived from chronic myelogeneous leukemia was observed among normal controls, non N-CWS-injected workers and N-CWS-injected workers. "
09/01/1983 - "[Adjuvant activity of Nocardia cell-wall skeleton on maintenance chemotherapy of acute non-lymphatic leukemia]."
01/01/1985 - "The present experiment indicates that combined treatment with N-CWS and CP effectively reduces induction of leukemia by ENU in rats, although other types of tumors were not affected."