711389-S

Also Known As:

1-(1-(2-(3-isopropylamino-2-hydroxypropoxy)-3,6-dichlorophenyl)vinyl)-1H-imidazole; 711389 S; S 1389; S-1389; 2-Propanol, 1-(3,6-dichloro-2-(1-(1H-imidazol-1-yl)ethenyl)phenoxy)-3-((1-methylethyl)amino)-, (2S-(2alpha,5alpha,6beta))-

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Amino Alcohols: 20
    - Propanolamines: 4
      - 711389-S: 3
- Alcohols: 595
  - Amino Alcohols: 20
    - Propanolamines: 4
      - 711389-S: 3
  - Propanols: 3
    - Propanolamines: 4
      - 711389-S: 3

Related Diseases

1.	Ventricular Premature Complexes (Premature Ventricular Contraction) 04/01/1988 - "Oral administration of 711389-S (10-30 mg/kg) in dogs markedly depressed the ventricular ectopic beats induced by coronary ligation. " 04/01/1988 - "711389-S (1-3 mg/kg, i.v.) decreased the number of ventricular extrasystoles induced by ouabain in dogs, and the doses of ouabain required to induce various types of arrhythmias were increased by pretreatment of guinea-pigs with intraduodenal application of 711389-S (5-10 mg/kg). " 04/01/1988 - "711389-S (1-3 mg/kg, i.v.) depressed arrhythmias induced by adrenaline and restored the sinus rhythm by significantly decreasing the number of ventricular ectopic beats induced by coronary ligation or occlusion in dogs. "
2.	Ventricular Fibrillation 08/01/1985 - "Increase of the ventricular fibrillation threshold by 711389-S, a new antiarrhythmic agent, in guinea-pigs." 08/01/1985 - "The increase of the ventricular fibrillation threshold (VFT) by 711389-S, a new antiarrhythmic agent, was compared with several other antiarrhythmic drugs using both in vitro (Langendorff) and in vivo preparations of guinea-pigs. "
3.	Premature Cardiac Complexes (Extrasystoles) 12/01/1989 - "Slowing of the ventricular and AV nodal conduction of extrasystoles with variable coupling intervals was also caused by S-1389. "
4.	Atrial Fibrillation 04/01/1988 - "Atrial fibrillation induced by a topical application of aconitine on the atrium was blocked by 711389-S (1 mg/kg, i.v.) in dogs. "

Related Drugs and Biologics

1.	Ouabain (G Strophanthin)
2.	Epinephrine (Adrenaline)
3.	Anti-Arrhythmia Agents
4.	Aconitine

Related Therapies and Procedures

1.	Ligation
2.	Oral Administration