complement C3d-k

a 43-kDa cleavage product of COMPLEMENT C3B; generated from the alpha chain of human iC3b by limited proteolysis with KALLIKREIN; resembles the C3d,g fragment; induces LEUKOCYTOSIS.

Also Known As:

C3d-k; complement 3d-k

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Immunoproteins: 43
      - Complement System Proteins: 33379
        Complement C3: 1636
        Complement C3b: 199
        complement C3d-k: 3
- Peptides: 82426
  - Peptide Fragments: 373
    - complement C3d-k: 3

Related Diseases

Leukocytosis (Pleocytosis)

03/10/1985 - "We have identified and synthesized a portion of C3d-K that is associated with the leukocytosis phenomenon. "
03/10/1985 - "A synthetic nonapeptide corresponding to the NH2-terminal sequence of C3d-K causes leukocytosis in rabbits."
06/01/1983 - "Thus, C3d-K exhibits two apparently independent functions, namely suppression of T cell proliferation and leukocytosis. "
07/01/1985 - "C3d-G, like C3d-K (a C3d fragment produced by the action of plasma kallikrein), was found to have bioactivities such as leukocytosis-inducing and immunosuppressive activities."
03/10/1985 - "We conclude that the nonapeptide TLDPERLGR represents the active center of the C3-derived leukocytosis factors C3e and C3d-K. "

Related Drugs and Biologics

1.	Mitogens
2.	Antigens
3.	Plasma Kallikrein
4.	complement C3e (C3e)