HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

1-octacosanol (octacosanol)

RN given refers to parent cpd
Also Known As:
octacosanol; 1-octacosanol, aluminum (1:3) salt; n-octacosanol; polycosanol
Networked: 25 relevant articles (3 outcomes, 8 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Guo, Tianyi: 3 articles (05/2022 - 05/2017)
2. Lin, Qinlu: 3 articles (05/2022 - 05/2017)
3. Luo, Feijun: 3 articles (05/2022 - 05/2017)
4. Bai, Jie: 2 articles (05/2022 - 07/2021)
5. Han, Shuai: 2 articles (05/2022 - 07/2021)
6. Hu, Zuomin: 2 articles (05/2022 - 07/2021)
7. Luo, Yi: 2 articles (05/2022 - 07/2021)
8. Xu, Wei: 2 articles (05/2022 - 05/2017)
9. Zhou, Yaping: 2 articles (05/2022 - 07/2021)
10. Wang, Tao: 2 articles (05/2012 - 07/2010)

Related Diseases

1. Obesity
2. Neoplasms (Cancer)
07/07/2008 - "The mechanism of inhibition of angiogenesis by octacosanol reflects on its effect on tumor angiogenesis and metastasis."
03/16/2016 - "In this study, PEG-derivatized octacosanol copolymer was successfully developed to improve the anti-tumor activity and eliminate toxicity of the commercial formulation of paclitaxel (PTX). "
07/07/2008 - "Our results showed that octacosanol (i) inhibits proliferation of endothelial cells and Ehrlich ascites tumor cells, (ii) inhibits neovascularization induced by angiogenic factors in chick chorioallantoic membrane and rat cornea in vivo angiogenesis assays, (iii) inhibits secretion of ascites fluid in the growing tumor cells in vivo. "
07/07/2008 - "Concerning the mechanism of action, octacosanol inhibited secretion of vascular endothelial growth factor into ascites fluid by the tumor cells. "
04/15/2013 - "Rice contains more than 100 bioactive substances including phytic acid, isovitexin, γ-oryzanol, phytosterols, octacosanol, squalene, γ-aminobutyric acid (GABA), tocopherol, tocotrienol derivatives, etc. Out of them, γ-oryzanol is known to have important biological profile such as anti-oxidants, inhibitor of cholesterol oxidation, reduce serum cholesterol levels in animals, effective in the treatment of inflammatory diseases, inhibit tumor growth, reduce blood pressure and promotes food storage stability when used as a food additive, etc. Hence in the present investigation, we aimed to evaluate the content and composition of γ-oryzanol from pigmented rice germplasms using a liquid chromatography with diode array detection and electrospray ionization-mass spectrometry (LC-DAD-ESI/MS). "
3. Parkinsonian Disorders (Parkinsonism)
4. Ulcerative Colitis
5. Fatigue

Related Drugs and Biologics

1. Phytosterols (Plant Sterols)
2. Cholesterol
3. Capsules (Microcapsules)
4. Tocotrienols
5. Tocopherols (Tocopherol)
6. Nerve Growth Factor (NGF)
7. Squalene
8. Phytic Acid (Inositol Hexaphosphate)
9. Maltose
10. Gum Arabic (Acacia, Gum)

Related Therapies and Procedures

1. Oral Administration