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3,4-disuccinyl 1,2-5,6-dianhydrogalactitol

structure given in first source

Also Known As:

1,2-5,6-dianhydrogalactitol bis(hydrogen butanedioate); 3,4-disuccinyldianhydrogalactitol

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Alcohols: 595
  - Sugar Alcohols: 143
    - Galactitol: 117
      - Dianhydrogalactitol: 75
        3,4-disuccinyl 1,2-5,6-dianhydrogalactitol: 3
Carbohydrates: 22023
- Sugar Alcohols: 143
  - Galactitol: 117
    - Dianhydrogalactitol: 75
      - 3,4-disuccinyl 1,2-5,6-dianhydrogalactitol: 3

Related Diseases

1.	Neoplasms (Cancer) 07/01/1989 - "[The effect of 3,4-disuccinyldianhydrogalactitol, N-nitrosourea and their combination on DNA synthesis in normal and mouse P388 tumor cells]." 01/01/1984 - "The rates of incorporation of 2-14C-thymidine into DNA of melanoma B16, bone marrow, gastrointestinal mucosa, spleen and liver at various time after administration of dianhydrogalactitol (DAG), 3,4-diacetyldianhydrogalactitol (DiacDAG) and 3,4-disuccinyldianhydrogalactitol (DisuDAG) at maxima nonlethal single doses to tumor-bearing mice were studied. " 10/01/1983 - "Cytostatic drugs under clinical trial [Elobromol (DBD), Myelobromol (DBM), Lycurim (LY), Zitostop (ZI)], others in preclinical analysis [dianhydrogalactitol (DAG), 3,4-diacetyldianhydrogalactitol (DiacDAG), 3,4-disuccinyldianhydrogalactitol (DisuDAG)], and compounds without any known antitumor effect in transplantable tumors [1-bromo-3,6-anhydrodulcitol (BAD), 1,2-epoxi-3,6-anhydrodulcitol (EAD)] were examined. "
2.	Experimental Melanoma 01/01/1984 - "The rates of incorporation of 2-14C-thymidine into DNA of melanoma B16, bone marrow, gastrointestinal mucosa, spleen and liver at various time after administration of dianhydrogalactitol (DAG), 3,4-diacetyldianhydrogalactitol (DiacDAG) and 3,4-disuccinyldianhydrogalactitol (DisuDAG) at maxima nonlethal single doses to tumor-bearing mice were studied. "
3.	Leukemia P388 07/01/1989 - "The rates of incorporation of 2-14C-thymidine into DNA of leukemia P388, bone marrow, gastrointestinal mucosa and spleen cells at various time after administration of 3,4-disuccinyldianhydrogalactitol (DisuDAG), 1-methyl-1-nitrosourea (MNU), 1-(2-hydroxyethyl)-3-(2-chloroethyl)-3-nitrosourea (HECNU) and their combinations at different doses to mice with leukemia P388 (solid form) were studied. "

Related Drugs and Biologics

1.	DNA (Deoxyribonucleic Acid)
2.	Dianhydrogalactitol
3.	Cytostatic Agents
4.	Mitobronitol
5.	mannosulfan (R-52)
6.	elmustine
7.	ritrosulfan