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Haemophilus influenzae type b polysaccharide vaccine (HIB-vaccine)

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Also Known As:

HIB-vaccine; CP-HIb vaccine; Haemophilus influenzae a, capsular polysaccharide vaccine; Haemophilus influenzae b, capsular polysaccharide vaccine; Haemophilus influenzae type b polyribosylribitol phosphate capsular polysaccharide vaccine

Networked: 208 relevant articles (10 outcomes, 33 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Slack, Mary P E: 6 articles (05/2011 - 01/2008)
2.	Booy, Robert: 5 articles (11/2011 - 01/2008)
3.	Heath, Paul T: 5 articles (11/2011 - 01/2008)
4.	Pollard, Andrew J: 5 articles (10/2010 - 04/2005)
5.	Gessner, Bradford D: 5 articles (06/2010 - 01/2005)
6.	Centers for Disease Control and Prevention (CDC): 4 articles (09/2011 - 08/2007)
7.	Griffiths, Ulla K: 4 articles (01/2011 - 07/2007)
8.	Jacquet, Jeanne-Marie: 4 articles (01/2010 - 10/2007)
9.	Ishiwada, Naruhiko: 3 articles (03/2015 - 09/2013)
10.	Hoshino, Tadashi: 3 articles (03/2015 - 09/2013)

Related Diseases

1.	Meningitis 05/01/2011 - "Hib vaccine appears to be highly effective in preventing Hib meningitis in Senegal." 12/01/2011 - "In those countries where Hib vaccine is a part of the routine infant immunization schedule, Hib has now been virtually eradicated as a cause of childhood meningitis. " 04/01/2008 - "Infant immunization with Hib vaccine has virtually eliminated Hib meningitis in Uganda within 5 years. " 12/01/2013 - "Using methods standardized during >20 years in the study site, clinical and microbiological surveillance for invasive Hib disease (primarily meningitis) in the Western Region of The Gambia from 2007 to 2010 was complemented with studies of Hib carriage in children aged 1 to <2 years, Hib antibody levels in children aged <5 years, and Hib vaccine coverage and timing in children aged 1 to <2 years. " 09/28/2004 - "Given the apparent Hib meningitis burden in Jeonbuk Province, additional studies to describe other invasive Hib syndromes, Hib-associated mortality and disability, and economic impact of Hib disease will be useful to guide public health decisions regarding routine Hib vaccine introduction."
2.	Pneumonia (Pneumonitis) 02/12/2014 - "We examined Hib vaccine herd protection against radiologically confirmed pneumonia among children less than 2 years old. " 09/01/2001 - "Our study indicates that a combined pneumococcal and Hib vaccine and a RSV vaccine would reduce the high rate of pneumonia in children under 5 years of age in Northeast Thailand." 07/01/2013 - "The effectiveness of Haemophilus influenzae type b (Hib) vaccine in preventing severe pneumonia in Asian children has been questioned, and many large Asian countries yet to introduce Hib conjugate vaccine in immunization programs. " 01/01/2005 - "These results do not support a major role for Hib vaccine in overall pneumonia-prevention programmes. " 01/01/2005 - "Hib vaccine did not prevent the great majority of pneumonia cases, including those with alveolar consolidation. "
3.	Infection 06/15/2001 - "Infant vaccination with conjugated Haemophilus influenzae type b (Hib) vaccine is highly effective in protecting against invasive Hib infections, but vaccine failures do occur. " 03/02/2010 - "This study describes the long-term complications in children with Haemophilus influenzae serotype b (Hib) vaccine failure and to determine their risk of other serious infections. " 05/01/2005 - "Based on the present data, the authors emphasize the need for more sensitive epidemiological and bacteriological studies aiming the improvement of the available Hib vaccine, in order to protect the susceptible population to infections due to other serological types of Hi and the reevaluation of immunization schedules used by the National Immunization Program." 03/01/2015 - "influenzae infections caused by NTHi, Hie, and Hif was reported in the countries where Hib vaccine had been widely used. " 05/01/2010 - "Prevention of Hib-infection using Act-HIB vaccine leads to decrease of acute respiratory disease rates and severity of infections. "
4.	Tetanus 05/01/1999 - "Local reactions were mild, but different between the four groups, a tetanus conjugate Hib vaccine showing the fewest reactions. " 03/26/1999 - "influenzae type B tetanus-conjugated (Act-HIB) vaccine, has been combined in a full liquid formulation with the whole-cell DTP. " 12/01/1994 - "However, combination with the Hib vaccine comprising polysaccharide conjugated to tetanus toxoid had dramatic effects on tetanus potency and immunogenicity when assayed in mice. " 04/19/2010 - "We estimated the sensitivity, i.e., the proportion of all cases of adverse events following immunization (AEFIs) reported to the Brazilian passive surveillance for adverse events following immunization (PSAEFI) with the diphtheria-tetanus-whole-cell pertussis-Haemophilus influenzae type b (DTwP/Hib) vaccine, as well as investigating factors associated with AEFIs reporting. " 01/01/2008 - "Safety and reactogenicity of a new heptavalent DTPw-HBV/Hib-MenAC (diphtheria, tetanus, whole cell pertussis-hepatitis B virus/Haemophilus influenzae type b-Neisseria meningitidis serogroups A and C) vaccine was compared with a widely used pentavalent DTPw-HBV/Hib vaccine. "
5.	Bacterial Meningitis 07/01/2008 - "To characterize the epidemiology, clinical features, and outcomes of acute bacterial meningitis, we subdivided our study into two time periods: the period prior to the routine use of Haemophilus influenzae type b (Hib) vaccine (1993-1998) and the period after the vaccine became available (1999-2003). " 02/01/2006 - "To study the changes in the epidemiology, clinical and bacteriological profiles of bacterial meningitis in the era of the Haemophilus influenzae type b (Hib)vaccine and pneumococcus resistance. " 08/01/2014 - "Hib vaccine and PCV7 decreased the rate of bacterial meningitis. " 08/01/2014 - "To investigate the trends in incidence and the characteristics of bacterial meningitis in Japan where Haemophilus influenzae type b (Hib) vaccine and 7-valent pneumococcal conjugated vaccine (PCV7) were introduced in 2008 and 2010, respectively, which was 5-20 years after their introduction in western countries. " 06/01/2010 - "Following use of Hib vaccine, pneumococcus has now become the most common etiology of pediatric acute bacterial meningitis in Dakar region. "

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