N-desmethylmethoxyphenamine (NDMP)

metabolite of methoxyphenamine; RN given refers to parent cpd without isomeric designation

Also Known As:

NDMP; (R)-isomer of N-desmethylmethoxyphenamine; (S)-isomer of N-desmethylmethoxyphenamine; 2-methoxyamphetamine; HCl of N-desmethylmethoxyphenamine; N-desmethylmethoxyphenamine hydrochloride; N-desmethylmethoxyphenamine, (+-)-isomer; N-desmethylmethoxyphenamine, (R)-isomer; N-desmethylmethoxyphenamine, (S)-isomer; N-desmethylmethoxyphenamine, sulfate (2:1); sulfate (2:1) of N-desmethylmethoxyphenamine

Networked: 6 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Ethylamines: 5
    - Phenethylamines: 28
      - Amphetamines: 717
        N-desmethylmethoxyphenamine: 6

Experts

1.	Guliani, Harminder: 2 articles (10/2021 - 01/2020)
2.	Hadjistavropoulos, Thomas: 2 articles (10/2021 - 01/2020)
3.	Jin, Shan: 2 articles (10/2021 - 01/2020)
4.	Lix, Lisa M: 1 article (10/2021)
5.	Hubbard, Tje: 1 article (07/2020)
6.	Ives, C: 1 article (07/2020)
7.	Cai, Shu-Ting: 1 article (01/2020)
8.	Chen, Hong-Peng: 1 article (01/2020)
9.	Deng, Lie-Hua: 1 article (01/2020)
10.	Hu, Wang-Wang: 1 article (01/2020)

Related Diseases

1.	Hypoxia (Hypoxemia) 04/01/2015 - "Moreover, either AIT or MCT effectively ameliorates neutrophil/NDMP-promoted TG by down-regulating expression of procoagulant factors during HE, which may reduce thrombotic risk evoked by hypoxia." 04/01/2015 - "Moreover, either AIT or MCT effectively ameliorates neutrophil/NDMP-promoted TG by down-regulating expression of procoagulant factors during HE, which may reduce thrombotic risk evoked by hypoxia. "
2.	Sepsis (Septicemia) 01/01/2020 - "NDMP levels were significantly increased in sepsis and septic shock patients with a parallel increase in pro-inflammatory mediators and sepsis severity score (p < 0.05) as well as mortality. " 01/01/2020 - "On days 1, 3 and 5 post-admission a series of data including plasma NDMP levels, patient demographics, TNF-α levels, IL-6 levels, sTREM-1 levels, and the sepsis severity score measurements were collected. " 08/09/2013 - "We conclude that the early production of TNF-α during sepsis can increase NDMP numbers through activation of the Caspase 8 pathway or NF-κB."
3.	Pain (Aches) 01/01/2020 - "Specifically, we contrasted LTC residents with daily pain or less than daily pain but with moderate or severe intensity (ie, clinically significant pain group; CSP) to residents with no pain or nondaily mild pain (NP/NDMP group). " 10/14/2021 - "We tested for differences in direct health care costs among long-term care (LTC) residents age 65 and older with clinically significant pain (CSP) and with no pain or non-daily mild pain (NP/NDMP). " 10/14/2021 - "The higher costs incurred by CSP residents compared to NP/NDMP residents are likely underestimated because pain problems are often missed in residents with dementia, who comprise a large portion of the LTC population. "
4.	Septic Shock (Toxic Shock Syndrome) 01/01/2020 - "NDMP levels were significantly increased in sepsis and septic shock patients with a parallel increase in pro-inflammatory mediators and sepsis severity score (p < 0.05) as well as mortality. "
5.	Neoplasm Metastasis (Metastasis) 07/01/2020 - "Patients with distant metastasis (DMp) compared with those without distant metastasis (NDMp) were associated with poorly differentiated tumours (DMp 62% vs NDMp 28%; p = 0.037), high-grade ductal carcinoma in situ (DMp 75% vs NDMp 39%; p = 0.043) and increased mean invasive tumour size (DMp 37mm vs NDMp 24mm; p = 0.014). "

Related Drugs and Biologics

1.	Caspase 8 (Caspase-8)
2.	Interleukin-6 (Interleukin 6)

Related Therapies and Procedures

1.	Long-Term Care