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denbufylline

structure given in first source

Also Known As:

7-(2'-oxopropyl)-1,3-di-n-butylxanthine; BRL 30892; BRL-30892

Networked: 8 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Xanthines: 123
    - denbufylline: 8
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purinones: 2
        Xanthines: 123
        denbufylline: 8

Related Diseases

1.	Peripheral Vascular Diseases (Peripheral Vascular Disease) 01/01/1984 - "The purpose of the present investigation was to study in animal experiments whether 7-(2'-oxopropyl)-1,3-di-n-butyl-xanthine (BRL 30892) could be of potential value for the treatment of peripheral vascular disease (PVD). "
2.	Dementia (Dementias) 11/01/1999 - "Denbufylline in dementia: a double-blind controlled study." 11/01/1999 - "The xanthine derivative denbufylline has been evaluated in the treatment of cognitive dysfunction in 110 patients with vascular or mixed dementia (VD) and 226 patients with dementia of the Alzheimer type (DAT). "
3.	Asthma (Bronchial Asthma) 02/01/1998 - "In this study, we investigated the direct effects of 8 clinically used anti-asthma drugs [salbutamol, salmeterol, theophylline, denbufylline, disodium cromoglycate (DSCG), azelastine, ketotifen and dexamethasone] on superoxide anions (O2-) and eosinophil peroxidase (EPO) release from human blood eosinophils in vitro. "
4.	Cognitive Dysfunction 11/01/1999 - "The xanthine derivative denbufylline has been evaluated in the treatment of cognitive dysfunction in 110 patients with vascular or mixed dementia (VD) and 226 patients with dementia of the Alzheimer type (DAT). "
5.	Multi-Infarct Dementia (Dementia, Multi Infarct) 07/01/1989 - "5. Denbufylline is being developed as an agent for the therapy of multi-infarct dementia. "

Related Drugs and Biologics

1.	Eosinophil Peroxidase
2.	Theophylline (Theon)
3.	Superoxides (Superoxide)
4.	Ketotifen (Ketotifene)
5.	Cromolyn Sodium (Cromoglicic Acid)
6.	Dexamethasone (Maxidex)
7.	Anions
8.	Albuterol (Salbutamol)
9.	Salmeterol Xinafoate (Serevent)
10.	azelastine (Optivar)

Related Therapies and Procedures

1.	Therapeutics