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poly I-5-mercapto-poly C

Also Known As:

poly I-MPC; polyinosinic acid-5-mercaptopolycytidylic acid

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Polynucleotides: 218
    - Polyribonucleotides: 23
      - Poly C: 296
        Poly I-C: 2220
        poly I-5-mercapto-poly C: 2
      - Poly I: 163
        Poly I-C: 2220
        poly I-5-mercapto-poly C: 2

Related Diseases

1.	Weight Loss (Weight Reduction) 09/01/1984 - "Weight loss and lethal and pyrogenic effects were markedly lower in Poly I-MPC treated animals than in those that received unmodified Poly I-Poly C. "
2.	Osteosarcoma (Osteogenic Sarcoma) 03/01/1991 - "Partially thiolated polycytidylic acid (5-mercaptopolycytidylic, MPC) and its double-stranded complex with polyinosinic acid [poly (I)].poly(I).MPC, were assayed in both antiproliferative and cytotoxicity tests against human cell lines: lung carcinoma A549, colon carcinoma HT-29, osteosarcoma HOS, and amnion cells (WISH). "
3.	Carcinoma (Carcinomatosis) 03/01/1991 - "Partially thiolated polycytidylic acid (5-mercaptopolycytidylic, MPC) and its double-stranded complex with polyinosinic acid [poly (I)].poly(I).MPC, were assayed in both antiproliferative and cytotoxicity tests against human cell lines: lung carcinoma A549, colon carcinoma HT-29, osteosarcoma HOS, and amnion cells (WISH). "

Related Drugs and Biologics

1.	Poly I
2.	Poly C
3.	Acids
4.	5-mercaptopolycytidylic acid