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succinyladenosine

found in body fluids of children with severe psychomotor delay & autism; RN given refers to (L)-isomer

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Adenosine: 12431
        succinyladenosine: 7
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Adenosine: 12431
      - succinyladenosine: 7
  - Ribonucleosides: 49
    - Adenosine: 12431
      - succinyladenosine: 7

Experts

1.	Cheng, Mei-Ling: 1 article (09/2018)
2.	Chiang, Meng-Han: 1 article (09/2018)
3.	Ho, Hung-Yao: 1 article (09/2018)
4.	Hung, Cheng-Yu: 1 article (09/2018)
5.	Lai, Ying-Chieh: 1 article (09/2018)
6.	Lin, Gigin: 1 article (09/2018)
7.	Lu, Kuan-Ying: 1 article (09/2018)
8.	Tsai, Cheng-Kun: 1 article (09/2018)
9.	Wu, Ren-Chin: 1 article (09/2018)
10.	Yeh, Ta-Sen: 1 article (09/2018)

Related Diseases

1.	Argininosuccinic Aciduria 04/01/1997 - "In a 15-month-old girl with profound hypotonia, we established the diagnosis of ASL deficiency by demonstrating succinyladenosine and SAICA riboside in urine and decreased residual activity of ASL in skin fibroblasts."
2.	Dihydropyrimidine Dehydrogenase Deficiency 10/20/1995 - "As this system permits the simultaneous determination of urinary orotic acid, uracil, dihydrouracil, pseudouridine, xanthine, 2,8-dihydroxyadenine and succinyladenosine, it offers a useful method for the detection of orotic aciduria, dihydropyrimidine dehydrogenase deficiency, dihydropyrimidinuria, xanthinuria, adenine phosphoribosyltransferase deficiency and adenylosuccinase deficiency."
3.	Neoplasms (Cancer) 09/07/2018 - "Compared with the adjacent healthy tissues, GC tumors demonstrated significantly higher aspartic acid, citicoline, glutamic acid, oxidized glutathione, succinyladenosine, and uridine diphosphate-N-acetylglucosamine levels, but significantly lower butyrylcarnitine, glutathione hydroxyhexanoycarnitine, inosinic acid, isovalerylcarnitine, and threonine levels (all P < 0.05). "
4.	Muscle Hypotonia (Hypotonia) 04/01/1997 - "In a 15-month-old girl with profound hypotonia, we established the diagnosis of ASL deficiency by demonstrating succinyladenosine and SAICA riboside in urine and decreased residual activity of ASL in skin fibroblasts."
5.	Inborn Errors Metabolism (Inborn Errors of Metabolism) 11/01/2013 - "Testing for succinyladenosine (S-Ado), a marker of ADSL deficiency, was incorporated into a screening panel for urine biomarkers for inborn errors of metabolism using electrospray tandem mass spectrometry. "

Related Drugs and Biologics

1.	Adenylosuccinate lyase deficiency
2.	SAICAR
3.	Xanthine
4.	Glutathione Disulfide (GSSG)
5.	Glutamic Acid (Glutamate)
6.	Biomarkers (Surrogate Marker)
7.	Uridine Diphosphate N-Acetylglucosamine
8.	Uracil
9.	Threonine (L-Threonine)
10.	Pseudouridine