acetochlor

09/01/2015 - "Use of acetochlor and cancer incidence in the Agricultural Health Study."
08/01/2000 - "Acetochlor-induced rat nasal tumors: further studies on the mode of action and relevance to humans."
09/01/2015 - "Among 33,484 men, there were 4,026 applicators who used acetochlor and 3,234 incident cancers, with 304 acetochlor-exposed cases. "
08/01/2000 - "This metabolic conversion could not be detected in 33 fresh human nasal tissue samples, supporting the earlier view that the acetochlor-induced rat nasal tumors do not represent a hazard for humans."
09/01/2015 - "We evaluated the use of acetochlor and cancer incidence among licensed pesticide applicators in the Agricultural Health Study. "

03/01/2020 - "This study was conducted to determine the effects of acetochlor on human liver carcinoma cells (HepG2), a cell model widely used to assess the potential for chemical hepatotoxicity. "
03/01/2020 - "Toxicity assessment of the herbicide acetochlor in the human liver carcinoma (HepG2) cell line."
10/01/2014 - "In the present study, the ability of herbicide acetochlor to affect a growth of estrogen-sensitive MCF-7 mammary epithelial carcinoma cells was studied using E-screen test. "

09/01/1996 - "The absence of genetic toxicity to the nasal epithelium of rats exposed acutely or subchronically to acetochlor favours a non-genotoxic mechanism for the induction of these adenomas. "
09/01/1996 - "Finally, microscopic nasal polypoid adenomas were induced in the rat when acetochlor was administered for two years at the maximum tolerated dose (MTD). "
08/01/2000 - "The herbicide acetochlor, and its analogue alachlor, have similar toxicological properties, the most significant being the induction of nasal adenomas in rats in 2-year feeding studies. "

09/20/2023 - "As the herbicide acetochlor (ACT) affects the plankton food web, this study investigated the effects of ACT and exocrine infochemicals from daphnids (after ACT exposure and/or starvation) on Scenedesmus obliquus growth, as well as the effects of ACT and starvation on life-history traits of Daphnia magna. "

09/01/1996 - "Despite some confusion caused by the early use of perilethal gavage administrations of acetochlor to rodents, and supra-MTD dietary concentrations in some of the chronic studies, the available MTD data are consistent with acetochlor not posing a genetic or carcinogenic hazard to humans."