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4- (3,7,11,15- tetramethyl- 6,10,14- hexadecatrienoyl)morpholine

structure given in first source

Also Known As:

E 0712; E-0712; (1,1'-Biphenyl)-4,4'-diol, 2,2',6,6'-tetrakis(1,1-dimethylethyl)-, (S)-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Oxazines: 9
    - Morpholines: 6
      - 4-(3,7,11,15-tetramethyl-6,10,14-hexadecatrienoyl)morpholine: 1

Related Diseases

1.

11/01/1984 - "These results suggest that E-0712 protects against liver injury, particularly hepatocellular necrosis, induced by D-galactosamine and carbon tetrachloride in rats."
11/01/1984 - "dose of D-galactosamine in which SGPT values and PT reached the peak within 48 hr. In cases in which a dose of carbon tetrachloride (i.p.) produced peak SGPT values and PT within 36 hr attenuation occurred likewise at 24, 36 and 60 hr. In the control and E-0712-treated rats dosed with D-galactosamine or carbon tetrachloride, SGPT values were positively correlated with PT at 24 hr. In addition, morphological degrees of acidophilic body formation or centrizonal necrosis were significantly reduced by E-0712. "

Related Drugs and Biologics

1.	Galactosamine
2.	Carbon Tetrachloride (Tetrachloromethane)
3.	Alanine Transaminase (SGPT)