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coumaran

Also Known As:

2,3-dihydrobenzofuran

Networked: 7 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzofurans: 26
      - coumaran: 7

Experts

1.	Wang, Haijun: 1 article (03/2022)
2.	Xin, Yang: 1 article (03/2022)
3.	Yu, Kaichen: 1 article (03/2022)
4.	Yu, Yang: 1 article (03/2022)
5.	Bakthavatsalam, Nandagopal: 1 article (01/2014)
6.	Raghavendra, Anjanappa: 1 article (01/2014)
7.	Rajashekar, Yallappa: 1 article (01/2014)
8.	Baba, Takahiko: 1 article (05/2003)
9.	Inagaki, Masanao: 1 article (05/2003)
10.	Iwatani, Kouji: 1 article (05/2003)

Related Diseases

1.	Edema (Dropsy) 05/29/2003 - "In this study, we discovered a novel skeleton, the 2,3-dihydrobenzofuran derivative, which inhibited PGE(2) production at a very low concentration and was effective in the anti-carrageenin footpad edema assay."
2.	Neoplasms (Cancer) 10/03/2023 - "Only the ethyl acetate extract of the callus culture influenced the cervical cancer cell line (HeLa) with an IC50 of 94.79 ± 2.0 µg/mL. From the ethyl acetate callus extract, 2,3-dihydrobenzofuran was isolated and purified and also evaluated against cancer cells. " 05/05/2023 - "In silico modeling was performed to investigate the binding orientation and affinity of the major identified compounds against Polo-like kinase (PLK1 protein) a cancer molecular target using molecular docking and molecular dynamic whereas eudesm-5-en-11-ol, piperitone, and 2,3-dihydrobenzofuran displayed better binding affinity and stability against PLK1 compared to the reference drug. "
3.	Ganglion Cysts (Ganglion) 01/01/2014 - "The in vivo inhibition was observed in both dose dependent and time dependent in case of housefly, and the nervous tissue (ganglion) and the whole insect homogenate of stored grain insect exposed to Coumaran. "
4.	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 08/05/2023 - "Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzofuran IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma."
5.	Wounds and Injuries (Trauma) 06/01/2000 - "TAK-218 has a 2,3-dihydrobenzofuran-5-amine (coumaran) structure which resembles alpha-tocopherol, and is a promising candidate as an agent for central nervous system (CNS) trauma and ischemia. "

Related Drugs and Biologics

1.	Prostaglandins E
2.	Carrageenan
3.	alpha-Tocopherol
4.	Biomarkers (Surrogate Marker)
5.	Vanillic Acid
6.	Phosphotransferases (Kinase)
7.	Kynurenic Acid (Kynurenate)
8.	Acids
9.	Polo-Like Kinase 1
10.	traumatic acid