MSH (11-13)

RN refers to (all-L)-isomer

Also Known As:

L-lysyl-L-prolyl-L-valine; Lys-Pro-Val; alpha-MSH (11-13)

Networked: 10 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Pituitary Hormones: 601
      - Anterior Pituitary Hormones: 187
        Pro-Opiomelanocortin: 1936
        Melanocortins: 946
        Melanocyte-Stimulating Hormones: 1119
        MSH (11-13): 10
    - Hypothalamic Hormones: 68
      - Pro-Opiomelanocortin: 1936
        Melanocortins: 946
        Melanocyte-Stimulating Hormones: 1119
        MSH (11-13): 10
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Nerve Tissue Proteins: 2
    - Neuropeptides: 6772
      - Melanocyte-Stimulating Hormones: 1119
        MSH (11-13): 10
      - Hypothalamic Hormones: 68
        Pro-Opiomelanocortin: 1936
        Melanocortins: 946
        Melanocyte-Stimulating Hormones: 1119
        MSH (11-13): 10
- Peptides: 82426

Experts

1.	Merlin, Didier: 2 articles (05/2016 - 03/2010)
2.	Huang, Lantian: 1 article (10/2021)
3.	Lin, Gaolong: 1 article (10/2021)
4.	Liu, Jiayi: 1 article (10/2021)
5.	Lu, Cuitao: 1 article (10/2021)
6.	Ran, Kunjie: 1 article (10/2021)
7.	Sun, Jie: 1 article (10/2021)
8.	Xu, He-Lin: 1 article (10/2021)
9.	Xue, Pengpeng: 1 article (10/2021)
10.	Yang, Jiaojiao: 1 article (10/2021)

Related Diseases

1.	Colitis 03/01/2010 - "We engineered nanoparticles (NPs) to deliver an anti-inflammatory tripeptide Lys-Pro-Val (KPV) to the colon and assessed its therapeutic efficacy in a mouse model of colitis. " 10/11/2021 - "KPV (Lys-Pro-Val), which is a tripeptide derived from α-MSH (α-melanocyte-stimulating hormone), has an anti-inflammatory effect on colitis. "
2.	Inflammation (Inflammations) 01/01/2000 - "In brief, alpha-MSH and certain of its fragments such as alpha-MSH [11-13] KPV modulate inflammation via three general actions: direct actions on peripheral host cells; actions on inflammatory cells within the brain to modulate local reactions; and descending neural anti-inflammatory pathways that control inflammation in peripheral tissues." 04/01/1994 - "alpha-Melanocyte-stimulating hormone (alpha-MSH1-13) and its COOH-terminal tripeptide alpha-MSH11-13 (Lys Pro Val) inhibit inflammation when administered systemically. " 03/01/1994 - "This peptide and a tripeptide that forms the COOH-terminal portion of the molecule (alpha-MSH11-13; Lys Pro Val) inhibit inflammation when given centrally or peripherally. "
3.	Carcinogenesis 05/01/2016 - "The use of an anti-inflammatory tripeptide KPV (Lys-Pro-Val) transported by PepT1 was able to prevent carcinogenesis in WT mice. "
4.	Wounds and Injuries (Trauma) 01/01/2013 - "The effect of α-MSH(11-13) on secondary lesion volume determined in cresyl violet stained sections (intraperitoneal injection 30 min after insult of 1 mg/kg α-MSH(11-13) or 0.9% NaCl) showed a considerable smaller trauma in α-MSH(11-13) injected mice. "
5.	Fever (Fevers) 07/01/1984 - "Effect of alpha-MSH 11-13 (lysine-proline-valine) on fever in the rabbit."

Related Drugs and Biologics

1.	Melanocyte-Stimulating Hormones (MSH)
2.	alpha-MSH
3.	Interleukin-1beta (Interleukin 1 beta)
4.	Valine (L-Valine)
5.	Proline (L-Proline)
6.	Peptides (Polypeptides)
7.	Oligopeptides
8.	Lysine (L-Lysine)
9.	Saline Solution
10.	cresyl violet

Related Therapies and Procedures

1.	Intraperitoneal Injections