beta-microseminoprotein

a major secretory protein from the human prostate gland; it contains 94 amino acids; inhibits FSH secretion with inhibin-like activity; and was previously designated as seminal plasma beta-inhibin

Also Known As:

MSMB protein, human; Msmb protein, mouse; Msmb protein, rat; PSP94 protein, human; PSP94 protein, rat; beta-inhibin, mouse; beta-microseminoprotein, human; beta-microseminoprotein, mouse; beta-microseminoprotein, rat; immunoglobulin-binding factor; microseminoprotein, beta protein, human; prostate secretory protein PSP94; prostate-specific protein-94; prostatic inhibin peptide; prostatic inhibin protein, mouse; prostatic inhibin-like peptide; prostatic secretory protein PSP94; seminal plasma prostatic inhibin; seminal plasma prostatic inhibin, human

Networked: 38 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Seminal Proteins: 8
    - Seminal Plasma Proteins: 25
      - Prostatic Secretory Proteins: 4
        beta-microseminoprotein: 38

Experts

1.	Lilja, Hans: 5 articles (02/2013 - 07/2007)
2.	Valtonen-André, Camilla: 3 articles (02/2013 - 08/2010)
3.	Vickers, Andrew J: 3 articles (02/2013 - 07/2007)
4.	Klein, Robert J: 3 articles (10/2010 - 05/2010)
5.	Haiman, Christopher A: 2 articles (02/2013 - 10/2010)
6.	Henderson, Brian E: 2 articles (02/2013 - 10/2010)
7.	Kolonel, Laurence N: 2 articles (02/2013 - 10/2010)
8.	Stram, Daniel O: 2 articles (02/2013 - 10/2010)
9.	Waters, Kevin M: 2 articles (02/2013 - 10/2010)
10.	Halldén, Christer: 2 articles (08/2010 - 05/2010)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 05/01/1998 - "Previous studies have shown that beta-microseminoprotein (beta-MSP) may be used as a diagnostic marker for prostate cancer. " 11/01/2019 - "The aim of this meta-analysis was to assess the association between beta-microseminoprotein gene (MSMB) rs10993994 polymorphism and prostate cancer (PCa) risk. " 02/06/2013 - "Levels of beta-microseminoprotein in blood and risk of prostate cancer in multiple populations." 10/01/2010 - "A common prostate cancer risk variant 5' of microseminoprotein-beta (MSMB) is a strong predictor of circulating beta-microseminoprotein (MSP) levels in multiple populations." 01/19/2010 - "MSMB, a gene coding for beta-microseminoprotein, has been identified as a candidate susceptibility gene for prostate cancer (PrCa) in two genome-wide association studies (GWAS). "
2.	Neoplasms (Cancer) 01/01/2021 - "Biodistribution studies showed favorable excretion pharmacokinetics with high tumor uptake in PC-3 or PC-3 prostatic inhibin peptide (PIP) tumor-bearing mice. " 11/01/1996 - "Immunoglobulin binding factor (IgBF) produced in the prostate is a useful marker for the diagnosis of prostatic tumor. " 04/01/2008 - "A number of genes identified have been shown to be associated with prostate disease and cancer, including beta-microseminoprotein (Msp) and tumor necrosis factor receptor superfamily 6 (Fadd). " 01/01/1994 - "Immunoglobulin binding factor: a new tumor marker for prostatic tumors." 09/01/1989 - "beta-Microseminoprotein may be as useful as gamma-seminoprotein in the pathologic examination of prostatic diseases, especially in histogenic classification of tumors or metastatic tumors. "
3.	Stomach Diseases 11/01/1997 - "The observations made have implications for the understanding of the differentiation of the mucosal cells in the antrum of the stomach and form a basis for future studies of beta-microseminoprotein in gastric disease."
4.	Carcinoma (Carcinomatosis) 12/01/1988 - "Serum and urinary prostatic inhibin-like peptide in benign prostatic hyperplasia and carcinoma of prostate." 01/01/1993 - "Beta-microseminoprotein immunoreactivity as a new prognostic indicator of prostatic carcinoma." 12/01/1988 - "The levels of immunoreactive prostatic inhibin-like peptide (PIP), having follicle-stimulating hormone suppressing properties, were estimated in the sera and urine samples of patients with benign prostatic hyperplasia (BPH) and prostatic carcinoma (PC) as compared to age-matched controls. " 07/16/1993 - "A comparative study on expression of prostatic inhibin peptide, prostate acid phosphatase and prostate specific antigen in androgen independent human and rat prostate carcinoma cell lines."
5.	Endometrial Neoplasms (Endometrial Cancer) 05/01/2000 - "Prostatic secretory protein (PSP94) expression in human female reproductive tissues, breast and in endometrial cancer cell lines." 03/01/2008 - "Loci on chromosome 10 include MSMB, which encodes beta-microseminoprotein, a primary constituent of semen and a proposed prostate cancer biomarker, and CTBP2, a gene with antiapoptotic activity; the locus on chromosome 7 is at JAZF1, a transcriptional repressor that is fused by chromosome translocation to SUZ12 in endometrial cancer. "

Related Drugs and Biologics

1.	Prostate-Specific Antigen (Semenogelase)
2.	Proteins (Proteins, Gene)
3.	Biomarkers (Surrogate Marker)
4.	Messenger RNA (mRNA)
5.	Antibodies
6.	Androgens
7.	Acid Phosphatase
8.	Prostatic Secretory Proteins
9.	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
10.	Tumor Biomarkers (Tumor Markers)