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3-nitropyrazole
structure given in first source
Also Known As:
DJW 94; DJW-94
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Pyrazoles: 61
3-nitropyrazole: 1
Related Diseases
1.
Neoplasms (Cancer)
01/01/1987 - "
A series of acetohydroxamic acid derivatives of 3-nitropyrazole were synthesized and evaluated for their ability to potentiate (chemosensitization) the activity of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) against EMT-6 mouse mammary tumor cells in vitro.
"
2.
Hypoxia (Hypoxemia)
01/01/1987 - "
Substitution of acetohydroxamic acid side chains at the N-1 position of the parent 3-nitropyrazole resulted in compounds which were preferentially toxic to cells treated under hypoxic conditions, and which were capable of enhancing the toxicity of CCNU in hypoxia.
"
Related Drugs and Biologics
1.
Lomustine (CCNU)
2.
acetohydroxamic acid (Lithostat)