deoxythymidylyl-3'-5'-deoxyadenylate (d(T-A))

Also Known As:

d(T-A); d(TA); (TpdA); 5'-phosphorylthymidylyl(3'-5')deoxyadenosine; d(pTpA); deoxy(thymidylyl-adenylyl); deoxythymidylyl-deoxyadenylic acid; thymidylyl-deoxyadenylic acid

Networked: 17 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Polynucleotides: 218
    - Oligonucleotides: 5145
      - Oligodeoxyribonucleotides: 2217
        deoxythymidylyl-3'-5'-deoxyadenylate: 17

Experts

1.	Angrisani, Antonio: 1 article (06/2022)
2.	Bianchi, Lorenzo: 1 article (06/2022)
3.	Cappabianca, Salvatore: 1 article (06/2022)
4.	Carbone, Salvatore Francesco: 1 article (06/2022)
5.	Clemente, Alfredo: 1 article (06/2022)
6.	Correale, Pierpaolo: 1 article (06/2022)
7.	Danti, Ginevra: 1 article (06/2022)
8.	Giacobbe, Giuliana: 1 article (06/2022)
9.	Grassi, Roberta: 1 article (06/2022)
10.	Grassi, Roberto: 1 article (06/2022)

Related Diseases

1.	Infections 10/01/2021 - "Moreover, TPDA shows high antibacterial activities against both gram-negative and gram-positive bacteria within a short time (10 min) of light irradiation and is found to efficiently protect fish from skin infections. " 09/30/2010 - "Phylogenetic analysis demonstrated that SRV-4 was distantly related to SRV-1, 2, 3, 5, 6 and 7. SRV/D-T, a new SRV/D recovered in 2005 from cynomolgus monkeys at Tsukuba Primate Center in Japan, clustered with the SRV-4 isolates from California and Texas and was shown to be another occurrence of SRV-4 infection. "
2.	Coronary Occlusion 07/01/1984 - "It is concluded that: 1) radioiodinated TPDA accurately reveals severely ischemic areas of myocardium without myocardial release of the radionuclide in coronary occlusions lasting 20 to 180 minutes and followed by reperfusion, and 2) double radiolabeled TPDA allows assessment of both occlusion and reperfusion flows. " 07/01/1984 - "The myocardial uptake of 15-(p-iodophenyl)-6- tellurapentadecanoic acid ( TPDA ) was studied in dogs during coronary occlusion and after reperfusion. " 07/01/1984 - "Dual radiolabeling of TPDA was employed in five Group A animals by intravenous injection of iodine-125 TPDA during coronary occlusion and iodine-131 TPDA after reperfusion. "
3.	Diffuse Scleroderma (Progressive Systemic Sclerosis) 02/27/1960 - "[Progressive scleroderma with considerable electromyographical changes treated with chelating agents (E.D.T.A.)]."
4.	Choroidal Neovascularization 10/01/2021 - "D-TA suppresses choroidal neovascularization significantly (by >80%, >50-fold better than free drug), attenuates inflammation in the choroid and retina, by limiting macrophage infiltration in the pathological area, significantly suppressing pro-inflammatory cytokines and pro-angiogenic factors, with minimal side effects to healthy ocular tissue and other organs. "
5.	Anti-Glomerular Basement Membrane Disease (Goodpasture's Syndrome) 12/01/2015 - "In fact, since the first experiences of TA in pregnancy for the prevention of hemolytic disease of the newborn, several diseases are at present treated with TA, mainly within 6 clinical categories: (a) TA is a priority and has no alternative equally effective treatment (e.g., thrombotic thrombocytopenic purpura); (b) TA is a priority but there are alternative therapies not contraindicated in pregnancy (e.g., myasthenia gravis); (c) TA is an effective tool of saving/avoiding drugs contraindicated in pregnancy (e.g., systemic lupus erythematosus); (d) TA is a treatment of specific conditions/complications of pregnancy with maternal and/or fetal risk (e.g., antiphospholipid syndrome); (e) TA is a treatment of specific conditions of pregnancy with exclusive fetal risk (e.g., hemolytic disease of the newborn); (f) TA is a treatment of disease which is strongly indicated and can exceptionally occur during pregnancy (e.g., Goodpasture's syndrome). "

Related Drugs and Biologics

1.	Keratin-13 (Keratin 13)
2.	Cytokines
3.	Radioisotopes (Radionuclides)
4.	Edetic Acid (EDTA)
5.	Chelating Agents
6.	Analgesics (Analgesic Drugs)
7.	Acids
8.	Carbon Fiber (Grafil)
9.	Iodine-131
10.	Iodine-125

Related Therapies and Procedures

1.	Neoadjuvant Therapy
2.	Patient-Controlled Analgesia (Analgesia, Patient Controlled)
3.	Therapeutics
4.	Intravenous Injections
5.	Analgesia