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preprogastrin

contains primary amino acid sequence of big gastrin extended at both the N- and C-terminus

Also Known As:

pre-progastrin

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chen, Wei-feng: 1 article (08/2008)
2.	Gao, Qian: 1 article (08/2008)
3.	He, Pei: 1 article (08/2008)
4.	Liao, Guo-qing: 1 article (08/2008)
5.	Liu, Lei: 1 article (08/2008)
6.	Liu, Peng-hui: 1 article (08/2008)
7.	Qu, Yi-mei: 1 article (08/2008)
8.	Song, Xiao-ming: 1 article (08/2008)
9.	Xu, Qing-wen: 1 article (08/2008)
10.	Yin, Yan-hui: 1 article (08/2008)

Related Diseases

1.	Neoplasms (Cancer) 12/01/2004 - "Multiple active products are generated from the precursor, preprogastrin, including the well-characterized amidated gastrins acting at the cholecystokinin-2 (CCK-2, or gastrin-CCK(B)) receptor, and others that may be growth factors in a range of cancers. " 08/08/2008 - "Peripheral blood mononuclear cells (PBMCs) from 134 lung cancer patients, 106 benign pulmonary disease, and 80 healthy individuals were isolated and assessed by nested reverse transcription-PCR assay for the expression of three different tumor markers, including tumor specific antigen 9 (TSA-9), Keratin 19 (KRT-19), and Pre-progastrin-releasing peptide (Pre-proGRP). "
2.	Thyroid Neoplasms (Thyroid Cancer) 05/01/1991 - "Expression and processing of human preprogastrin in murine medullary thyroid carcinoma cells."
3.	Lung Neoplasms (Lung Cancer) 08/08/2008 - "Peripheral blood mononuclear cells (PBMCs) from 134 lung cancer patients, 106 benign pulmonary disease, and 80 healthy individuals were isolated and assessed by nested reverse transcription-PCR assay for the expression of three different tumor markers, including tumor specific antigen 9 (TSA-9), Keratin 19 (KRT-19), and Pre-progastrin-releasing peptide (Pre-proGRP). "
4.	Lung Diseases (Lung Disease) 08/08/2008 - "Peripheral blood mononuclear cells (PBMCs) from 134 lung cancer patients, 106 benign pulmonary disease, and 80 healthy individuals were isolated and assessed by nested reverse transcription-PCR assay for the expression of three different tumor markers, including tumor specific antigen 9 (TSA-9), Keratin 19 (KRT-19), and Pre-progastrin-releasing peptide (Pre-proGRP). "
5.	Insulinoma 11/01/1998 - "Hamster insulinoma cells were stably transfected with wild-type rat preprogastrin and phosphorylation site mutants; biosynthesis was studied by a pulse-chase protocol. "

Related Drugs and Biologics

1.	Keratin-19 (Keratin 19)
2.	Intercellular Signaling Peptides and Proteins (Growth Factors)
3.	Tumor Biomarkers (Tumor Markers)
4.	Messenger RNA (mRNA)
5.	Peptides (Polypeptides)
6.	Gastrins
7.	Antigens
8.	pro-gastrin-releasing peptide (31-98)

Related Therapies and Procedures

1.	CHASE protocol