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musk tibetine (musk tibetene)
in contrast to other musk cpds this cpd does not cause allergic photocontact dermatitis; structure given in first source
Also Known As:
musk tibetene
; 2,6-dinitro-3,4,5-trimethyl-tert-butylbenzene
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Nitrobenzenes: 7
Dinitrobenzenes: 187
musk tibetine: 4
Nitro Compounds: 66
Nitrobenzenes: 7
Dinitrobenzenes: 187
musk tibetine: 4
Related Diseases
1.
Phototoxic Dermatitis (Phototoxicity)
02/01/1986 - "
Musk tibetene and musk moskene were negative for phototoxicity, photoallergenicity and contact sensitivity under the test conditions.
"
02/01/1986 - "
The potential of 4 related nitro musk substances (musk tibetene, musk ketone, musk xylol, and musk moskene) to cause photoallergy, phototoxicity, and/or contact sensitivity was compared to that of musk ambrette, a known photoallergen.
"
2.
Photoallergic Dermatitis (Photoallergy)
02/01/1986 - "
The potential of 4 related nitro musk substances (musk tibetene, musk ketone, musk xylol, and musk moskene) to cause photoallergy, phototoxicity, and/or contact sensitivity was compared to that of musk ambrette, a known photoallergen.
"
3.
Hypersensitivity (Allergy)
10/01/1985 - "
A patient with photocontact allergy to musk ambrette was investigated with patch and photopatch testing with dilutions of musk ambrette and 4 other nitro-musk compounds (musk ketone, moskene, musk tibetine, musk xylene) as well as with in vitro ultraviolet-irradiated solutions of musk ambrette.
"
4.
Hepatocellular Carcinoma (Hepatoma)
03/14/1997 - "
Musk xylene, musk ketone, musk ambrette, musk moskene and musk tibetene revealed no genotoxicity in the micronucleus test with human lymphocytes and with the human hepatoma cell line Hep G2.
"
03/14/1997 - "
The nitro musk compounds musk xylene (1-tert.-butyl-3,5-dimethyl-2,4,6-trinitrobenzene), musk ketone (4-tert.-butyl-3,5-dinitro-2,6-dimethylacetophenone), musk ambrette (1-tert.-butyl-4-methyl-6-methoxy-3,5-dinitrobenzene), musk moskene (1,1,3,3,5-pentamethyl-4,6-dinitroindane) and musk tibetene (1-tert.-butyl-3,4,5-trimethyl-2,6-dinitrobenzene) were tested for their genotoxic activity in the micronucleus test (MN) with human lymphocytes in vitro and the human hepatoma cell line Hep G2.
"
5.
Contact Dermatitis (Eczema, Contact)
02/01/1986 - "
Musk tibetene and musk moskene were negative for phototoxicity, photoallergenicity and contact sensitivity under the test conditions.
"
02/01/1986 - "
The potential of 4 related nitro musk substances (musk tibetene, musk ketone, musk xylol, and musk moskene) to cause photoallergy, phototoxicity, and/or contact sensitivity was compared to that of musk ambrette, a known photoallergen.
"
Related Drugs and Biologics
1.
moskene
2.
musk ketone
3.
musk xylene
4.
musk ambrette (artificial)
5.
musk