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epidermal growth factor precursor

Also Known As:

prepro-EGF; pro-EGF

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chen, Rui: 1 article (01/2017)
2.	Jin, Ge: 1 article (01/2017)
3.	McIntyre, Thomas M: 1 article (01/2017)
4.	Brown, Michael S: 1 article (12/2002)
5.	Deisenhofer, Johann: 1 article (12/2002)
6.	Goldstein, Joseph L: 1 article (12/2002)
7.	Henderson, Keith: 1 article (12/2002)
8.	Henry, Lisa: 1 article (12/2002)
9.	Ichtchenko, Konstantin: 1 article (12/2002)
10.	Rudenko, Gabby: 1 article (12/2002)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2017 - "Biotinylating platelet surface proteins showed ADAMDEC1 hydrolyzed surface pro-EGF to HMW-EGF that stimulated HeLa EGF receptor (EGFR) reporter cells and EGFR-dependent tumor cell migration. " 10/01/1991 - "Northern analysis in polyadenylated RNA from 15 EGFR(+) cancers using pretransforming growth factor alpha (pre-TGF alpha), prepro-EGF complementary DNA, and pE7, a complementary DNA clone of human EGFR, as probes revealed that pre-TGF alpha and EGFR mRNAs but not prepro-EGF mRNA were expressed in all cases examined. "
2.	Renal Cell Carcinoma (Grawitz Tumor) 01/01/1992 - "These data correlate with our previous findings that pro-EGF gene expression is decreased in human renal carcinoma and support the concept that low-molecular-weight urinary EGF is derived from high-molecular-weight kidney pro-EGF." 07/01/1990 - "We have analyzed the expression of the genes for the precursors of epidermal growth factor (pro-EGF) and transforming growth factor alpha (proTGF-alpha) as well as for the EGF receptor in tissue specimens of a large number of adult patients with renal cell carcinoma. "
3.	Autosomal Dominant Polycystic Kidney (ADPKD) 03/01/1995 - "The majority of simple and autosomal dominant polycystic kidney disease renal cysts contained high sodium ion concentration, epidermal growth factor precursor protein and Tamm-Horsfall protein, characteristic of the early thick ascending limb. "
4.	Leiomyoma (Uterine Fibroids) 07/01/1994 - "Northern blot hybridization using 32P-labeled human prepro-EGF complementary DNA was carried out for nonpregnant human endometria from hysterectomized uteri of leiomyoma, decidua from early pregnancy, and in vitro decidualized endometrial cells by medroxyprogesterone acetate (MPA). "
5.	Hypertrophy 01/01/1989 - "Also, there is a relatively late increase in prepro EGF mRNA levels in TALH and DCT cells during the process of renal hypertrophy. "

Related Drugs and Biologics

1.	Epidermal Growth Factor (EGF)
2.	ErbB Receptors (EGF Receptor)
3.	Complementary DNA (cDNA)
4.	Transforming Growth Factor alpha (TGF-alpha)
5.	Messenger RNA (mRNA)
6.	Uromodulin
7.	Intercellular Signaling Peptides and Proteins (Growth Factors)
8.	Medroxyprogesterone Acetate (Depo-Provera)
9.	Sodium
10.	Proteins (Proteins, Gene)