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sakyomicin A
from strain of Nocardia; structure given in first source
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Quinones: 434
Benzoquinones: 25
sakyomicin A: 2
Related Diseases
1.
Non-Hodgkin Lymphoma (Lymphosarcoma)
04/01/1986 - "
Among the naphthoquinones tested, juglone (5-hydroxy-1,4-naphthoquinone) which resembles the partial structure of sakyomicin A was the most active in cytotoxicity against murine lymphosarcoma L5178Y cells, electron acceptor function in the oxidation of NADH by Clostridium kluyveri diaphorase or rat liver mitochondria and inhibition against avian myeloblastosis virus reverse transcriptase.
"
2.
Acquired Immunodeficiency Syndrome (AIDS)
04/01/1986 - "
Inhibition by sakyomicin A of avian myeloblastosis virus reverse transcriptase and proliferation of AIDS-associated virus (HTLV-III/LAV).
"
Related Drugs and Biologics
1.
RNA-Directed DNA Polymerase (Reverse Transcriptase)
2.
Naphthoquinones
3.
NAD (NADH)
4.
juglone