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succinimidyl 4-(4-maleimidophenyl)butyrate

structure given in first source

Also Known As:

PS50 cpd; SMPB

Networked: 11 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Imides: 79
  - Succinimides: 11
    - succinimidyl 4-(4-maleimidophenyl)butyrate: 11
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - Pyrrolidinones: 162
      - Succinimides: 11
        succinimidyl 4-(4-maleimidophenyl)butyrate: 11

Experts

1.	Lin, Donghai: 1 article (10/2017)
2.	Liu, Yindi: 1 article (10/2017)
3.	Liu, Zhao: 1 article (10/2017)
4.	Meng, Chun: 1 article (10/2017)
5.	Yang, Juanjuan: 1 article (10/2017)
6.	Chakraborty, Trinad: 1 article (04/2017)
7.	Frantz, Renate: 1 article (04/2017)
8.	Linne, Uwe: 1 article (04/2017)
9.	Mraheil, Mobarak Abu: 1 article (04/2017)
10.	Teubner, Lisa: 1 article (04/2017)

Related Diseases

1.	Bacterial Infections (Bacterial Infection) 11/01/2013 - "We conclude that SsrA and SmpB are important for persister survival and may serve as a good target for developing new antibiotics that kill persister bacteria for improved treatment of persistent bacterial infections."
2.	Infections 04/01/2017 - "In the present study, we assessed the contribution of SmpB to the growth and virulence of Listeria monocytogenes, a human intracellular food-borne pathogen that colonizes host tissues to cause severe invasive infections. " 11/01/2013 - "We found that disruption of one, or both, of the smpB or ssrA genes significantly decreased the virulence of the APEC strain E058, as assessed by chicken infection assays. " 01/01/2017 - "Targeting Inhibition of SmpB by Peptide Aptamer Attenuates the Virulence to Protect Zebrafish against Aeromonas veronii Infection." 03/01/2010 - "The smpB-ssrA mutant of Yersinia pestis functions as a live attenuated vaccine to protect mice against pulmonary plague infection."
3.	Tuberculosis (Tuberculoses) 09/15/2014 - "tuberculosis SmpB that is expressed in E. " 10/01/2017 - "tuberculosis SmpB (MtSmpB, spanning residues 4-133) protein determined by a suite of 2D/3D heteronuclear NMR experiments along with predicted the secondary structure." 10/01/2017 - "Thus, elucidation of molecular details and dynamic properties of the SmpB-tmRNA interaction is a crucial step towards effectively blocking trans-translation process to shorten the duration of tuberculosis treatment. "
4.	Starvation 12/01/2001 - "Housekeeping genes that were upregulated during starvation of both wild-type and relA mutant strains included the newly identified T-box members of the aminoacyl-tRNA synthetase genes, the genes for components of the tmRNA-mediated peptide tagging and proteolysis system for abnormal proteins (ssrA, smpB, clpP, and clpC), and the operons for the dnaK and groE groups of molecular chaperones. "
5.	Respiratory Tract Infections (Respiratory Tract Infection) 09/01/2015 - "Comparison of Established Diagnostic Methodologies and a Novel Bacterial smpB Real-Time PCR Assay for Specific Detection of Haemophilus influenzae Isolates Associated with Respiratory Tract Infections."

Related Drugs and Biologics

1.	Anti-Bacterial Agents (Antibiotics)
2.	Proteins (Proteins, Gene)
3.	Peptides (Polypeptides)
4.	tmRNA
5.	Molecular Chaperones (Chaperone, Molecular)
6.	Attenuated Vaccines
7.	Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)
8.	hemopexin receptor
9.	3,3'-dithiobis(sulfosuccinimidyl propionate)
10.	disuccinimidyl suberate