naphthalene 1,2-oxide

Also Known As:

naphthalene oxide

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

1.	Lung Injury 01/01/1991 - "To investigate the role of circulating reactive metabolites in lung injury, the stability, metabolism and cytotoxicity of naphthalene oxide, a reactive intermediate, were examined in the perfused mouse lung. " 06/01/1995 - "Naphthalene is converted into naphthalene oxide and the circulation of this reactive metabolite from the liver to lung is a possible mechanism for lung injury. "
2.	Carcinogenesis 10/15/2001 - "The species difference may be due to a combination of higher levels of naphthalene oxide in the mouse lung and a greater susceptibility of the mouse lung to epoxide-induced carcinogenesis. "
3.	Necrosis 01/01/1991 - "Histologic examination of the lungs fixed 4 hr after infusion of naphthalene oxide (0.25-1.0 mumol/60 min) revealed selective vacuolation and necrosis of Clara cells, significant decreases in the mass of bronchiolar Clara cells and increases in the mass of vacuolated cells. "