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2'-chlorophenethylamine
structure given in first source
Also Known As:
beta-chlorophenethylamine; Benzeneethanamine, beta-chloro-, (11beta,16alpha)-
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Ethylamines: 5
Phenethylamines: 28
2'-chlorophenethylamine: 1
Related Diseases
1.
Dehydration (Water Stress)
06/25/1984 - "
Mechanistically significant findings presented herein include: 1) an analysis of primary deuterium isotope effects on turnover, indicating major differences in rate-determining steps for beta-chloro- and beta- hydroxyphenethylamine hydroxylation, Dkcat = 6.1 and 1.0, respectively; 2) evidence that dehydration of the gem-diol derived from oxygen- 18-labeled beta- hydroxyphenethylamine hydroxylation occurs in a random manner, attributed to dissociation of enzyme-bound gem-diol prior to alpha-aminoacetophenone formation; 3) the observation of a deuterium isotope effect for beta- chlorophenethylamine inactivation, Dkinact = 3.7, implicating C--H bond cleavage in the inactivation process; and 4) the demonstration that alpha-aminoacetophenone can replace ascorbic acid as exogenous reductant in the hydroxylation of tyramine.
"
Related Drugs and Biologics
1.
Reducing Agents
2.
2-Hydroxyphenethylamine
3.
Tyramine
4.
Oxygen (Dioxygen)
5.
Isotopes
6.
Enzymes
7.
Deuterium
8.
Ascorbic Acid (Vitamin C)
9.
phenacylamine