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3- carboxy- 4- methyl- 5- propyl- 2- furanpropionic acid

structure in first source

Also Known As:

3-carboxy-4-methyl-5-propyl-2-furanpropionate; CMPFPA; 2-Furanpropanoic acid, 3-carboxy-4-methyl-5-propyl-, (2S-(2alpha,3beta,4aalpha,12balpha))-

Networked: 8 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Furans: 85
    - 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid: 8
Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Propionates: 988
      - 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid: 8
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Propionates: 988
      - 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid: 8

Experts

1.	Deguchi, Tsuneo: 2 articles (02/2006 - 04/2005)
2.	Otagiri, Masaki: 2 articles (02/2006 - 04/2005)
3.	Terasaki, Tetsuya: 2 articles (02/2006 - 04/2005)
4.	Alvarez, Jean Claude: 1 article (04/2022)
5.	Caskey, Fergus J: 1 article (04/2022)
6.	Chesnaye, Nicholas C: 1 article (04/2022)
7.	Dekker, Friedo W: 1 article (04/2022)
8.	Drechsler, Christiane: 1 article (04/2022)
9.	EQUAL study investigators: 1 article (04/2022)
10.	Evans, Marie: 1 article (04/2022)

Related Diseases

1.	Muscular Diseases (Myopathy) 09/03/2014 - "The purpose of this study was to determine the effect of four uremic toxins-hippuric acid, 3-carboxy-4-methyl-5-propyl-2-furanpropionate, indole-3-acetic acid, and 3-indoxyl sulfate-on statin-induced myopathy. "
2.	Renal Insufficiency (Renal Failure) 04/01/2005 - "Evidence suggests that uremic toxins such as hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS), and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF) promote the progression of renal failure by damaging tubular cells via rat organic anion transporter 1 (rOat1) and rOat3 on the basolateral membrane of the proximal tubules. "
3.	Chronic Renal Insufficiency 11/27/2020 - "A surface-enhanced Raman scattering-based approach for rapid and highly sensitive quantitative analysis of 3-carboxy-4-methyl-5-propyl-2-furanpropionate and indole-3-acetic acid in saline, human serum and uremic serum of patients with chronic kidney disease." 11/27/2020 - "3-Carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF) and indole-3-acetic acid (IAA) are critical protein-bound uremic toxins that occur during chronic kidney disease (CKD). "
4.	Uremia 02/01/2001 - "In this article, we review the characteristics and consequences of changes in protein binding in uremia, as well as the toxicity of the protein-bound uremic solutes 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid (CMPF), indoxyl sulfate, hippuric acid, homocysteine, and p-cresol. "
5.	Fatigue 04/01/2022 - "Only trimethylamine N-oxide (TMAO; positive association with fatigue), p-cresyl sulfate (PCS) with constipation and 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid (negative association with shortness of breath) demonstrated moderately strong associations with symptoms in adjusted analyses. "

Related Drugs and Biologics

1.	Uremic Toxins
2.	indoleacetic acid (indole acetic acid)
3.	hippuric acid
4.	Sulfates (Sulfates, Inorganic)
5.	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)
6.	Proteins (Proteins, Gene)
7.	Indican
8.	Organic Anion Transporters
9.	Urea (Carbamide)
10.	Proline (L-Proline)

Related Therapies and Procedures

1.	Continuous Ambulatory Peritoneal Dialysis (CAPD)