3-hydroxy-7-methylcholanoic acid (HMCA)

structure given in first source

Also Known As:

HMCA; 3 alpha-hydroxy-7 epsilon-methyl-5 beta-cholanoic acid; 7-methyllithocholic acid; Cholan-24-oic acid, 3-hydroxy-7-methyl-, (3alpha,5beta)-

Networked: 9 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Bile Acids and Salts: 11432
      - Cholic Acids: 14
        Lithocholic Acid: 316
        3-hydroxy-7-methylcholanoic acid: 9
    - Cholanes
      - Cholic Acids: 14
        Lithocholic Acid: 316
        3-hydroxy-7-methylcholanoic acid: 9

Experts

1.	Kawakami, Hideaki: 1 article (05/2019)
2.	Kimura, Ikuo: 1 article (05/2019)
3.	Kuboshima, Toru: 1 article (05/2019)
4.	Kuwahara, Hiroshige: 1 article (05/2019)
5.	Masujima, Yuki: 1 article (05/2019)
6.	Miyamoto, Junki: 1 article (05/2019)
7.	Nishitani, Yosuke: 1 article (05/2019)
8.	Ohue-Kitano, Ryuji: 1 article (05/2019)
9.	Taira, Satsuki: 1 article (05/2019)
10.	Watanabe, Keita: 1 article (05/2019)

Related Diseases

1.	Weight Gain 05/09/2019 - "In this study, we demonstrated that dietary HMCA was efficacious against HFD-induced weight gain and hepatic steatosis, and that it improved insulin sensitivity. "
2.	Insulin Resistance 05/09/2019 - "In this study, we demonstrated that dietary HMCA was efficacious against HFD-induced weight gain and hepatic steatosis, and that it improved insulin sensitivity. " 05/09/2019 - "Collectively, these results suggest that HMPA derived from HMCA is metabolically beneficial, and regulates hepatic lipid metabolism, insulin sensitivity, and the gut microbial community. "
3.	Stroke (Strokes) 09/07/2017 - "The HTI was composed of 4 items: Alberta Stroke Program Early CT score (ASPECTS), National Institutes of Health Stroke Scale (NIHSS), hyperdense MCA (HMCA) sign, and AF on electrocardiogram (ECG) at admission. " 01/01/2001 - "Balanced kappa statistics for both the HMCA and the MCA dot sign were in the moderate to good range when the stroke symptom side was given. " 01/01/2001 - "Two neuroradiologists and 2 stroke neurologists initially blinded to all clinical information and then with knowledge of the affected hemisphere evaluated scans for the presence of the MCA dot sign, the HMCA sign, and early MCA territory ischemic changes. " 01/01/2017 - "The assessed variables were the type of stroke classification, the presence of contraindications to the tPA administration, the presence of a hyperdense intracranial artery sign (HMCA), and the Alberta Stroke Program Early CT Score (ASPECTS) score. "
4.	Thrombosis (Thrombus) 11/01/2003 - "The MCA dot sign has been proposed to indicate thrombosis of M2 or M3 MCA branches, analogous to the hyperdense middle cerebral artery (HMCA) sign indicating M1 thrombosis. " 01/01/2006 - "HMCA sign on post-Gd T1WI is highly specific and moderately sensitive indicator of acute thrombus with M1 MCA segment, as validated by angiography. "
5.	Cerebral Infarction 01/01/2001 - "The hyperdense appearance of the main middle cerebral artery (HMCA) is now a familiar early warning of large cerebral infarction, brain edema, and poor prognosis. " 11/01/1997 - "We could demonstrate the following early signs of cerebral infarction: focal hypodensity (23.2%), obscuration of basal ganglia (12.6%), focal brain swelling (22.1%), hyperdense middle cerebral artery sign (HMCA; 11.5%). "

Related Drugs and Biologics

1.	Hydrogels
2.	Indicators and Reagents (Reagents)
3.	Hempa (Hexamethylphosphoramide)
4.	Adenine

Related Therapies and Procedures

1.	Contraindications